Hydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats.
This animal study examined Hydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 12 weeks. The abstract reports: ELISA assay showed hydrogen-rich saline lowered the levels of pro-inflammatory cytokines (IL-8 and IL-6) and anti-inflammatory cytokine IL-10 in bronchoalveolar lavage fluid and serum…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats.
This animal study examined Hydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen-rich saline attenuates lung injury induced by intestinal I/R. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice.
This animal study examined Hydrogen gas inhalation protects against cigarette smoke-induced COPD development in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: These findings demonstrated that H inhalation could inhibit CS-induced COPD development in mice, which is associated with reduced ERK1/2 and NF-κB-dependent inflammatory responses. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway.
This uncontrolled human study examined Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway. The abstract describes Human participants. The abstract reports: The results indicated that 2% H gas treatment increased the survival rates, decreased the W/D weight ratio and the lung injury score, alleviated the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Inhalation Attenuates Seawater Instillation-Induced Acute Lung Injury via the Nrf2 Pathway in Rabbits.
This animal study examined Hydrogen Gas Inhalation Attenuates Seawater Instillation-Induced Acute Lung Injury via the Nrf2 Pathway in Rabbits. The abstract describes Rabbit model; hydrogen delivered as hydrogen inhalation. The abstract reports: These results demonstrate that hydrogen gas inhalation attenuates seawater instillation-induced acute lung injury in rabbits and that the protective effects observed may be related…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor.
This animal study examined Hydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: High concentrations of hydrogen could ameliorate pulmonary dysfunction, airway mucus hypersecretion, oxidation damage, and inflammation response in rats exposed to concentrated ambient PM2.5. Additionally,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice.
This animal study examined Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Molecular hydrogen exhibited a protective effect on the LIR-induced ALI model. Hydrogen decreased malondialdehyde and increased superoxide dismutase activity in lung tissues. Additionally, hydrogen…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice.
This animal study examined High concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice. The abstract describes Mouse model. The abstract reports: HCH can effectively alleviate LPS-induced ALI, which may be related to activation of Nrf2 signaling pathway and inhibition of inflammatory response and cell apoptosis…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEvaluation of the therapeutic effects of nebulized inhalation of hydrogen-rich water on primary blast lung injury in C57BL/6 mice.
This animal study examined Evaluation of the therapeutic effects of nebulized inhalation of hydrogen-rich water on primary blast lung injury in C57BL/6 mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The overpressure generated by blasts leads to alveolar and capillary damage, resulting in ventilation-perfusion mismatch and increased intrapulmonary shunting. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEvaluation of the effect of enriched hydrogen saline solution on distant organ (lung) damage in skeletal muscle ischemia reperfusion in rats.
This animal study examined Evaluation of the effect of enriched hydrogen saline solution on distant organ (lung) damage in skeletal muscle ischemia reperfusion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS at a dose of 20 mg/kg, administered intraperitoneally 30 min before ischemia in rats, reduced lipid peroxidation and oxidative stress, while also reducing IR damage…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich saline on aquaporin 1, 5 in septic rat lungs.
This uncontrolled human study examined Effects of hydrogen-rich saline on aquaporin 1, 5 in septic rat lungs. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreConsumption of hydrogen water reduces paraquat-induced acute lung injury in rats.
This animal study examined Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water and hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that hydrogen water ameliorated these alterations, demonstrating that hydrogen water alleviated paraquat-induced acute lung injury possibly by inhibition of oxidative damage. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHigh Concentration Hydrogen Mitigates Sepsis-Induced Acute Lung Injury in Mice by Alleviating Mitochondrial Fission and Dysfunction.
This animal study examined High Concentration Hydrogen Mitigates Sepsis-Induced Acute Lung Injury in Mice by Alleviating Mitochondrial Fission and Dysfunction. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Lungs are among the organs that are affected in MOF, resulting in acute lung injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation attenuates lung contusion after blunt chest trauma in mice.
This animal study examined Hydrogen inhalation attenuates lung contusion after blunt chest trauma in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen inhalation therapy significantly mitigated inflammatory responses associated with lung contusion in mice. Hydrogen inhalation therapy may be a supplemental therapeutic strategy for treating…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice.
This animal study examined Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response most probably through the TLR4-NF-κB pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
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