Hydrogen gas with extracorporeal cardiopulmonary resuscitation improves survival after prolonged cardiac arrest in rats.
This uncontrolled human study examined Hydrogen gas with extracorporeal cardiopulmonary resuscitation improves survival after prolonged cardiac arrest in rats. The abstract describes Human participants. The abstract reports: H therapy improved mortality in highly lethal CA rats rescued by ECPR and helped recover brain electrical activity. The underlying mechanism might be linked…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress.
This uncontrolled human study examined Protective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline can exert a protective effect against TBI via reducing oxidative stress. Molecular hydrogen may be a more effective therapeutic strategy for TBI…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management
This animal study examined Hydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: H2 inhalation was beneficial when begun after ROSC, even when delivered in the absence of hyperoxia. Combined TTM and H2 inhalation was more effective…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of hydrogen gas on the survival rate of mice following global cerebral ischemia.
This animal study examined Effect of hydrogen gas on the survival rate of mice following global cerebral ischemia. The abstract describes Mouse model; sample size 12. The abstract reports: Global cerebral ischemia and reperfusion (I/R) often result in high mortality. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats.
This animal study examined Hydrogen gas ameliorates oxidative stress in early brain injury after subarachnoid hemorrhage in rats. The abstract describes Rat model; reported duration 2 hrs. The abstract reports: Hydrogen gas could exert its neuroprotective effect against early brain injury after subarachnoid hemorrhage by its antioxidative activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtection of the endothelium and endothelial glycocalyx by hydrogen against ischaemia-reperfusion injury in a porcine model of cardiac arrest.
This animal study examined Protection of the endothelium and endothelial glycocalyx by hydrogen against ischaemia-reperfusion injury in a porcine model of cardiac arrest. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation. The abstract reports: In pigs, hydrogen gas inhalation during CPR and post-resuscitation care was associated with less pronounced metabolic acidosis compared to controls. However, we could not…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline—A Novel Neuroprotective Agent in a Mouse Model of Experimental Cerebral Ischemia via the ROS-NLRP3 Inflammasome Signaling Pathway In Vivo and In Vitro
Our previous research revealed that inflammation plays an important role in the pathophysiology of cerebral ischemia. The function of the NOD-like receptor protein 3 (NLRP3) inflammasome is to activate the inflammatory process. Recent findings suggest that reactive oxygen species (ROS) are essential secondary messengers that activate the NLRP3 inflammasome.
Read MoreHydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats.
Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular disease with poor clinical outcome. Nucleotide binding and oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome serves a key role in inflammatory response, which may lead to endothelial cell injury and blood-brain barrier (BBB) disruption. Hydrogen (H) is considered a neuroprotective antioxidant.
Read MoreLongitudinal multiparametric MRI study of hydrogen-enriched water with minocycline combination therapy in experimental ischemic stroke in rats.
This animal study examined Longitudinal multiparametric MRI study of hydrogen-enriched water with minocycline combination therapy in experimental ischemic stroke in rats. The abstract describes Rat model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of high concentration hydrogen gas improves short-term outcomes in a rat model of asphyxia induced-cardiac arrest
This animal study examined Inhalation of high concentration hydrogen gas improves short-term outcomes in a rat model of asphyxia induced-cardiac arrest. The abstract describes Rat model; reported duration 1 hour. The abstract reports: Findings of this preclinical study suggest that water electrolysis-derived 60% hydrogen gas may improve short-term outcomes in cardiogenic global brain hypoxia-ischemia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBeneficial effects of hydrogen-rich saline on early burn-wound progression in rats.
This animal study examined Beneficial effects of hydrogen-rich saline on early burn-wound progression in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen can attenuate early wound progression following deep burn injury. The beneficial effect of hydrogen was mediated by attenuating oxidative stress, which inhibited apoptosis…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of hydrogen-rich saline on ischemia/reperfusion injury in rat skin flap.
This animal study examined Protective effect of hydrogen-rich saline on ischemia/reperfusion injury in rat skin flap. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our findings suggest that HRS mitigates I/R injury by decreasing inflammation and, therefore, has the potential for application as a therapy for improving skin…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePreconditioning with one-time hydrogen gas does not attenuate skin flap ischemia-reperfusion injury in rat models.
This animal study examined Preconditioning with one-time hydrogen gas does not attenuate skin flap ischemia-reperfusion injury in rat models. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Preconditioning with one-time inhaled hydrogen does not attenuate skin flap IR injuries in rat models. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model.
This animal study examined Hydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results of this study support the hypothesis that oral administration of hydrogen-rich water benefits the wound healing process by decreasing oxidative stress and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC/Nga Mice.
This animal study examined The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC/Nga Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 25 days. The abstract reports: The results suggest that HW affects allergic contact dermatitis through modulation of Th1 and Th2 responses in NC/Nga mice. This is an automated editorial draft based on the abstract and requires source review before publication.
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