Hydrogen-related enhancement of in vivo antioxidant ability in the brain of rats fed coral calcium hydride.
This animal study examined Hydrogen-related enhancement of in vivo antioxidant ability in the brain of rats fed coral calcium hydride. The abstract describes Rat model; reported duration 4 weeks. The abstract reports: These results clarify the mechanism that CCH may exert antioxidant activity by significantly enhancing the basal endogenous antioxidant ability in the hippocampus through a…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSubseafloor microbial communities in hydrogen-rich vent fluids from hydrothermal systems along the Mid-Cayman Rise.
This study examined Subseafloor microbial communities in hydrogen-rich vent fluids from hydrothermal systems along the Mid-Cayman Rise. The abstract reports: There was little overlap in the phylotypes found at each site, although similar and dominant hydrogen-utilizing genera were present at both. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRe: Preventive Effect of Hydrogen Water on the Development of Detrusor Overactivity in a Rat Model of Bladder Outlet Obstruction: N. Miyazaki, O. Yamaguchi, M. Nomiya, K. Aikawa and J. Kimura J Urol 2016;195:780-787.
Re: Preventive Effect of Hydrogen Water on the Development of Detrusor Overactivity in a Rat Model of Bladder Outlet Obstruction: N. Miyazaki, O. Yamaguchi, M.
Read MoreAlkaline Water and Longevity: A Murine Study.
Two groups of mice received alkaline water for three years—one produced by a water ionizer and one prepared from a concentrated alkaline solution—while controls received tap water. Survival analyses suggested longer lifespan in the alkaline-water groups, and histological examination found no treatment-specific organ pathology. These results are preclinical and suggest the therapeutic potential of a water-ionizer intervention relevant to molecular hydrogen. The study did not include a reported dissolved-H₂ concentration, so it cannot establish that molecular hydrogen caused the survival findings. Further human research is needed to establish clinical effectiveness.
Read MoreProtective effect of hydrogen-rich saline on decompression sickness in rats.
Hydrogen-rich saline reduced decompression-sickness incidence and associated lung and spinal-cord injury markers in rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
Read MoreAtomic hydrogen surrounded by water molecules, H(H2O)m, modulates basal and UV-induced gene expressions in human skin in vivo.
This animal study examined Atomic hydrogen surrounded by water molecules, H(H2O)m, modulates basal and UV-induced gene expressions in human skin in vivo. The abstract describes Animal model. The abstract reports: We found that H(H2O)m prevented UV-induced ROS generation and inhibited UV-induced MMP-1, COX-2 and IL-6 expressions, and UV-induced JNK and c-Jun phosphorylation in HaCaT…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects immunocytes from radiation-induced apoptosis.
The researchers found that H₂-rich medium pretreatment reduced •OH level in AHH-1 cells. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.
Read MoreHydrogen-rich water as a modulator of gut microbiota?
This publication examined hydrogen-rich water using the study design reported by the authoritative source. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreAn Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress
Corneal alkali burns are potentially blinding injuries. Alkali induces oxidative stress in corneas followed by excessive corneal inflammation, neovascularization, and untransparent scar formation. Molecular hydrogen (H), a potent reactive oxygen species (ROS) scavenger, suppresses oxidative stress and enables corneal healing when applied on the corneal surface.
Read MoreTherapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage.
This animal study examined Therapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage. The abstract describes Rabbit model. The abstract reports: We previously found that UVB irradiation of the cornea caused the imbalance between the antioxidant and prooxidant enzymes in the corneal epithelium, followed by…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen saline treatment attenuates hyperoxia-induced retinopathy by inhibition of oxidative stress and reduction of VEGF expression.
This animal study examined Hydrogen saline treatment attenuates hyperoxia-induced retinopathy by inhibition of oxidative stress and reduction of VEGF expression. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 5 days. The abstract reports: Hydrogen saline may be a potential treatment for hyperoxia-induced retinopathy that acts via the inhibition of oxidative stress and the reduction of VEGF expression. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen improves type 2 diabetes through inhibiting oxidative stress.
This animal study examined Molecular hydrogen improves type 2 diabetes through inhibiting oxidative stress. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen; reported duration 4 weeks. The abstract reports: The results showed that in rats with T2DM, molecular hydrogen treatment decreased fasting blood glucose levels, increased hepatic glycogen synthesis and improved insulin sensitivity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress.
This animal study examined Molecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress. The abstract describes Rabbit model. The abstract reports: Results show that irrigation of the damaged eyes with H solution immediately after the injury and then within next five days renewed corneal transparency…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen treatment prevents lipopolysaccharide-induced pulmonary endothelial cell dysfunction through RhoA inhibition.
This in vitro or cellular study examined Hydrogen treatment prevents lipopolysaccharide-induced pulmonary endothelial cell dysfunction through RhoA inhibition. The abstract describes Endothelial cell model. The abstract reports: Our findings suggest that RhoA is a crucial protein in the signaling pathway of LPS-induced endothelial cell dysfunction. Hydrogen treatment can prevent LPS-induced junctional…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective Effects of Hydrogen on Myocardial Mitochondrial Functions in Septic Mice.
This animal study examined Protective Effects of Hydrogen on Myocardial Mitochondrial Functions in Septic Mice. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
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