Effects of perioperative hydrogen inhalation on brain edema and prognosis in patients with glioma.

This 2025 opinion article comments on the separate 2024 single-center randomized trial of perioperative hydrogen/oxygen inhalation after glioma surgery. It discusses methodological reporting, generalizability, clinical significance, follow-up, mechanism, dosing, cost and future trial design; it does not report a new patient cohort or intervention.

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