Hydrogen gas promotes apoptosis of lung adenocarcinoma A549 cells through X-linked inhibitor of apoptosis and baculoviral inhibitor of apoptosis protein repeat-containing 3.

This uncontrolled human study examined Hydrogen gas promotes apoptosis of lung adenocarcinoma A549 cells through X-linked inhibitor of apoptosis and baculoviral inhibitor of apoptosis protein repeat-containing 3. The abstract describes Human participants; hydrogen delivered as injected or infused hydrogen. The abstract reports: Hydrogen gas has been found to affect a variety of diseases; however, the effect of hydrogen gas on patients with lung cancer has not…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas therapy induced shrinkage of metastatic gallbladder cancer: A case report.

This case report or case series examined Hydrogen gas therapy induced shrinkage of metastatic gallbladder cancer: A case report. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: This is the first report of an efficacy and safety study about hydrogen therapy in patient with metastatic GBC and a critical general condition,…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas improves photothermal therapy of tumor and restrains the relapse of distant dormant tumor.

This animal study examined Hydrogen gas improves photothermal therapy of tumor and restrains the relapse of distant dormant tumor. The abstract describes Mouse model. The abstract reports: Inflammation during photothermal therapy (PTT) of tumor usually results in adverse consequences. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas inhibits lung cancer progression through targeting SMC3.

This uncontrolled human study examined Hydrogen gas inhibits lung cancer progression through targeting SMC3. The abstract describes Human participants. The abstract reports: Results showed that H inhibited cell viability, migration and invasion, and catalyzed cell apoptosis and H induced A549 and H1975 cells G2/M arrest. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas represses the progression of lung cancer via down-regulating CD47.

This animal study examined Hydrogen gas represses the progression of lung cancer via down-regulating CD47. The abstract describes Mouse model. The abstract reports: In our previous study, our project group found that H2 could decrease the expression of CD47 in lung cancer A549 cells via the next-generation…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Suppression of autophagy facilitates hydrogen gas-mediated lung cancer cell apoptosis.

This in vitro or cellular study examined Suppression of autophagy facilitates hydrogen gas-mediated lung cancer cell apoptosis. The abstract describes A549 cell model. The abstract reports: Our previous study found that hydrogen gas (H) could efficiently inhibit lung cancer progression; however, the underlying mechanisms still remains to be elucidated. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis.

This uncontrolled human study examined Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis. The abstract describes Human participants; sample size 55; hydrogen delivered as hydrogen inhalation. The abstract reports: Exhausted cluster of differentiation (CD)8+ T cells lose immunological activity due to mitochondrial dysfunction caused by peroxisome proliferator‑activated receptor γ coactivator 1α (PGC‑1α) inactivation, resulting in…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension

This animal study examined Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension. The abstract describes Rat model. The abstract reports: Our findings suggest that chronic H gas inhalation may help prevent LV hypertrophy in hypertensive DS rats. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas reduces chronic intermittent hypoxia‐induced hypertension by inhibiting sympathetic nerve activity and increasing vasodilator responses via the antioxidation

This animal study examined Hydrogen gas reduces chronic intermittent hypoxia‐induced hypertension by inhibiting sympathetic nerve activity and increasing vasodilator responses via the antioxidation. The abstract describes Rat model; reported duration 5 weeks. The abstract reports: We found that the systolic and diastolic blood pressure (BP) increased significantly in rats exposed to intermittent hypoxia, both of which were markedly attenuated…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension

This animal study examined Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension. The abstract describes Rat model. The abstract reports: A recent clinical study demonstrated that haemodialysis with a dialysate containing hydrogen (H) improves blood pressure control in end-stage kidney disease. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas protects against ovariectomy-induced osteoporosis by inhibiting NF-κB activation.

This animal study examined Hydrogen gas protects against ovariectomy-induced osteoporosis by inhibiting NF-κB activation. The abstract describes Mouse model. The abstract reports: H2 markedly inhibited RANKL-induced activation, nuclear translocation, and transcriptional activity of NF-κB (P  These results demonstrated that H2 could be an effective therapeutic agent…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models.

This animal study examined Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models. The abstract describes Mouse model; reported duration 60 days. The abstract reports: These results suggest that H therapy can mitigate toxic metabolites in the astrocytic urea cycle, thereby reducing neurodegeneration and memory loss in AD. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic Inhalation of Hydrogen Gas for Alzheimer’s Disease Patients and Subsequent Long-Term Follow-Up as a Disease-Modifying Treatment: An Open Label Pilot Study.

This uncontrolled human study examined Therapeutic Inhalation of Hydrogen Gas for Alzheimer’s Disease Patients and Subsequent Long-Term Follow-Up as a Disease-Modifying Treatment: An Open Label Pilot Study. The abstract describes Human participants; reported duration 6 months. The abstract reports: To objectively assess the neuron integrity, diffusion tensor imaging (DTI) with advanced magnetic resonance imaging (MRI) was applied to neuron bundles passing through the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress

This in vitro or cellular study examined Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress. The abstract describes Keratinocyte model. The abstract reports: In the present study, HO dose-dependently impaired the adenosine triphosphate (ATP)-induced Ca response, which was partially protected via co-treatment with β-mercaptoethanol, resulting in reduced…. This is an automated editorial draft based on the abstract and requires source review before publication.

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