Dissolved molecular hydrogen (H) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity.
This uncontrolled human study examined Dissolved molecular hydrogen (H) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity. The abstract describes Human participants. The abstract reports: H-dissolved PD solutions could preserve mesothelial cells and peritoneal membrane integrity in PD rats. Clinical application of H in PD could be a novel…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline against renal ischemia-reperfusion injury by increased expression of heme oxygenase-1 in aged rats.
This animal study examined Protective effects of hydrogen-rich saline against renal ischemia-reperfusion injury by increased expression of heme oxygenase-1 in aged rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS improves the renal response to I/R in aged rats, possibly by reducing oxidative stress and upregulating HO-1 gene expression. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreOrgan preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs.
This animal study examined Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs. The abstract describes Porcine model; hydrogen delivered as injected or infused hydrogen; reported duration 4 hours. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAerosol inhalation of a hydrogen-rich solution restored septic renal function.
This animal study examined Aerosol inhalation of a hydrogen-rich solution restored septic renal function. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Promotes the Recovery of Renal Function after Ischemia/Reperfusion Injury in Rats via Anti-apoptosis and Anti-inflammation.
This animal study examined Hydrogen-Rich Saline Promotes the Recovery of Renal Function after Ischemia/Reperfusion Injury in Rats via Anti-apoptosis and Anti-inflammation. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRSS showed a protective effect in the prevention of renal injury and could promote renal function recovery after I/R injury in rats. HRSS might…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates acute renal injury in sodium taurocholate-induced severe acute pancreatitis by inhibiting ROS and NF-κB pathway.
This animal study examined Hydrogen-rich saline attenuates acute renal injury in sodium taurocholate-induced severe acute pancreatitis by inhibiting ROS and NF-κB pathway. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Results showed that hydrogen-rich saline attenuated the following: (1) serum Cr and BUN, (2) pancreatic and renal pathological injuries, (3) renal MDA, (4) renal…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats.
This animal study examined Pretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Pretreatment by HRS ameliorated renal dysfunction in glycerol-induced rhabdomyolysis by inhibiting oxidative stress and the inflammatory response. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice.
This animal study examined Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice. The abstract describes Mouse model; reported duration 5 days. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Alleviates Kidney Fibrosis Following AKI and Retains Klotho Expression.
This animal study examined Hydrogen-Rich Saline Alleviates Kidney Fibrosis Following AKI and Retains Klotho Expression. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline; reported duration 28 day. The abstract reports: Histological data showed that the HRS treatment significantly decreased the fibrosis in renal tissues when compared with the IR group, and both of BUN…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury
This animal study examined Inhalation of 4% and 67% hydrogen ameliorates oxidative stress, inflammation, apoptosis, and necroptosis in a rat model of glycerol-induced acute kidney injury. The abstract describes Rat model; hydrogen delivered as injected or infused hydrogen. The abstract reports: After 72 hours of glycerol injection (8 mL/kg), we found that glycerol triggered oxidative stress, inflammatory reactions, and apoptotic events. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stress
This animal study examined Hydrogen-rich saline attenuates eosinophil activation in a guinea pig model of allergic rhinitis via reducing oxidative stress. The abstract describes Animal model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: HRS may play a protective role in attenuating allergic inflammation, and suppressing the increase and activation of eosinophils in AR possibly through antioxidation effect…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model.
This uncontrolled human study examined Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model. The abstract describes Human participants; reported duration 60 min. The abstract reports: Recently, it has been suggested that hydrogen gas (H2) exerts a therapeutic antioxidant activity by selectively reducing hydroxyl radical (•OH, the most cytotoxic reactive…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreH2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain.
This animal study examined H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. The abstract describes Rat model. The abstract reports: We found that H2 clearly inhibited hyperalgesia and allodynia in neuropathic pain and also attenuated the pro-inflammatory cytokines TNF-α, IL-1β, and high-mobility group box…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAnti-inflammation effects of hydrogen saline in LPS activated macrophages and carrageenan induced paw oedema.
This in vitro or cellular study examined Anti-inflammation effects of hydrogen saline in LPS activated macrophages and carrageenan induced paw oedema. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: As a more convenient way than inhaling H2, hydrogen saline exhibits a protective effect against inflammation and it might provide a novel therapeutic approach…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model
This uncontrolled human study examined Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model. The abstract describes Human participants. The abstract reports: The results showed that the inhalation of H (2%) or hyperoxia (98%) alone improved the 14-day survival rate of ZY-challenged mice from 20 to…. This is an automated editorial draft based on the abstract and requires source review before publication.
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