Hydrogen gas treatment prolongs replicative lifespan of bone marrow multipotential stromal cells in vitro while preserving differentiation and paracrine potentials.
This animal study examined Hydrogen gas treatment prolongs replicative lifespan of bone marrow multipotential stromal cells in vitro while preserving differentiation and paracrine potentials. The abstract describes Animal model. The abstract reports: Interestingly, 3% hydrogen gas treatment did not decrease hydroxyl radical, protein carbonyl, and 8-hydroxydeoxyguanosine, suggesting that scavenging hydroxyl radical might not be responsible for…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen exerts neuroprotection by activation of the miR‐21/PI3K/AKT/GSK‐3β pathway in an in vitro model of traumatic brain injury
This in vitro or cellular study examined Hydrogen exerts neuroprotection by activation of the miR‐21/PI3K/AKT/GSK‐3β pathway in an in vitro model of traumatic brain injury. The abstract describes PC12 cell model. The abstract reports: The results showed that hydrogen-rich medium improved neurite regeneration and inhibited apoptosis in the injured cells. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death.
This animal study examined Hydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death. The abstract describes Animal model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. The abstract reports: Hydrogen gas inhalation during EVLP improved donation after cardiac death lung function via reduction of inflammation and apoptosis, and this effect persisted after LTx. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of dissolved molecular hydrogen against hydrogen peroxide-, hydroperoxide-, and glyoxal-induced injuries to human skin keratinocytes
This in vitro or cellular study examined Protective effects of dissolved molecular hydrogen against hydrogen peroxide-, hydroperoxide-, and glyoxal-induced injuries to human skin keratinocytes. The abstract describes HaCaT keratinocyte model. The abstract reports: Our results showed that H exerted cytoprotective effects against stress induced by HO, t-BuOOH, and glyoxal. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAntioxidant Activity of Hydrogen Nanobubbles in Water with Different Reactive Oxygen Species both in Vivo and in Vitro.
This animal study examined Antioxidant Activity of Hydrogen Nanobubbles in Water with Different Reactive Oxygen Species both in Vivo and in Vitro. The abstract describes Animal model; hydrogen delivered as hydrogen water. The abstract reports: Using a relatively weak reduced dye, APF, we showed that hydrogen NB water can effectively remove three cytotoxic ROS, OH, ClO, and ONOO, from…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro.
This uncontrolled human study examined Protective effect of hydrogen-rich medium against high glucose-induced apoptosis of Schwann cells in vitro. The abstract describes Human participants. The abstract reports: HG was found to induce severe oxidative stress and promote the caspase‑dependent and caspase‑independent apoptosis of SCs. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNew Approach in Translational Medicine: Effects of Electrolyzed Reduced Water (ERW) on NF-κB/iNOS Pathway in U937 Cell Line under Altered Redox State.
This in vitro or cellular study examined New Approach in Translational Medicine: Effects of Electrolyzed Reduced Water (ERW) on NF-κB/iNOS Pathway in U937 Cell Line under Altered Redox State. The abstract describes Cell culture / in vitro model. The abstract reports: Several findings indicate that ERW had the ability of a scavenger free radical, which results from hydrogen molecules with a high reducing ability and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Flush After Cold Storage as a New End-Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury.
This in vitro or cellular study examined Hydrogen Flush After Cold Storage as a New End-Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreElectrolyzed Hydrogen Water Protects against Ethanol-Induced Cytotoxicity by Regulating Aldehyde Metabolism-Associated Enzymes in the Hepatic Cell Line HepG2.
This in vitro or cellular study examined Electrolyzed Hydrogen Water Protects against Ethanol-Induced Cytotoxicity by Regulating Aldehyde Metabolism-Associated Enzymes in the Hepatic Cell Line HepG2. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: In this study, we found that EHW inhibits ethanol-induced cytotoxicity by decreasing the intracellular acetaldehyde, a toxic substance produced by ethanol degradation, in hepatocyte…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model.
This uncontrolled human study examined Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model. The abstract describes Human participants; sample size 4; reported duration 6 hours. The abstract reports: Hydrogen exposure significantly reduced collagen (p = 0.01), TRAP-6 (p = 0.04), and ADP-induced (p = 0.04) platelet aggregation and showed a trend toward…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water attenuates the radiotoxicity induced by tritium exposure in vitro and in vivo.
This animal study examined Hydrogen-rich water attenuates the radiotoxicity induced by tritium exposure in vitro and in vivo. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Results showed that intragastric administration of HRW effectively promoted the elimination of urinary tritium, decreased the level of serum tritium and tissue-bound tritium (OBT),…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreA Comprehensive Analysis of the Electrolytic Hydrogen Water Mechanism via a Feedforward Loop and its Functional Role in Intestinal Cells In Vitro
This in vitro or cellular study examined A Comprehensive Analysis of the Electrolytic Hydrogen Water Mechanism via a Feedforward Loop and its Functional Role in Intestinal Cells In Vitro. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: Highlights Identification of Novel Key Regulatory Genes Modulated by Electrolytic Hydrogen Water (EHW) Treatment: PPI network analysis demonstrated that EHW downregulates mitochondrial oxidative metabolism-related…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Medium Ameliorates Lipopolysaccharides-Induced Mitochondrial Fission and Dysfunction in Human Umbilical Vein Endothelial Cells (Huvecs) via Up-Regulating HO-1 Expression
This uncontrolled human study examined Hydrogen-Rich Medium Ameliorates Lipopolysaccharides-Induced Mitochondrial Fission and Dysfunction in Human Umbilical Vein Endothelial Cells (Huvecs) via Up-Regulating HO-1 Expression. The abstract describes Human participants. The abstract reports: It has been showed that the change of mitochondrial dynamics has been proved to be one of the main causes of death in patients…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreH2 inhibits TNF-α-induced lectin-like oxidized LDL receptor-1 expression by inhibiting nuclear factor κB activation in endothelial cells
This animal study examined H2 inhibits TNF-α-induced lectin-like oxidized LDL receptor-1 expression by inhibiting nuclear factor κB activation in endothelial cells. The abstract describes Mouse model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period.
This in vitro or cellular study examined The Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period. The abstract describes Endothelial cell model; reported duration 4 hours. The abstract reports: Hydrogen-attenuated inflammatory response in a PMVECs lung transplantation model during cold storage. The effect may be achieved by inhibition of p38 MAPK and NF-κB…. This is an automated editorial draft based on the abstract and requires source review before publication.
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