Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury.
This animal study examined Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Hydrogen treatment resulted in significantly improved gastrointestinal transit, as well as jejunal smooth muscle contractility in response to bethanechol. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-enriched preservation protects the isogeneic intestinal graft and amends recipient gastric function during transplantation.
This animal study examined Hydrogen-enriched preservation protects the isogeneic intestinal graft and amends recipient gastric function during transplantation. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Graft preloading with hydrogen demonstrated superior morphologic and functional graft protection in rodent intestinal transplantation, ultimately facilitating recipient survival. Antioxidant capacity and muscularis heme…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline on necrotizing enterocolitis in neonatal rats.
This animal study examined Protective effects of hydrogen-rich saline on necrotizing enterocolitis in neonatal rats. The abstract describes Rat model; sample size 11; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS showed beneficial effects on neonatal rats with NEC via decreasing oxidative stress, increasing antioxidant capacity, suppressing inflammation, and preserving mucosal integrity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline on ulcerative colitis rat model.
This animal study examined Protective effects of hydrogen-rich saline on ulcerative colitis rat model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Antioxidative hydrogen-rich saline effectively protected the rats from UC, which might be, at least in part, because of inhibition of vascular endothelial growth factor. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle.
This animal study examined Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle. The abstract describes Rat model; reported duration 3 weeks. The abstract reports: We showed that 8-OHdG, but not MDA, significantly increased by 149% and 145% in HU-NW and HU-AEW, respectively, when compared with CONT. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline.
This animal study examined MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Collectively, miR-199a-3p may serve a key role in the anti-apoptotic mechanism of HRS that contributes to its protection of the intestine against I/R injury. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation therapy alone may not alleviate intestinal mucosal damage in NOMI without total‐layer necrosis: An experimental swine model study
This animal study examined Hydrogen inhalation therapy alone may not alleviate intestinal mucosal damage in NOMI without total‐layer necrosis: An experimental swine model study. The abstract describes Porcine model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Although critically ill conditions can trigger NOMI, the model used in this study did not involve transmural necrosis. Under such conditions, hydrogen inhalation therapy…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways.
This animal study examined Hydrogen-Rich Water Mitigates LPS-Induced Chronic Intestinal Inflammatory Response in Rats via Nrf-2 and NF-κB Signaling Pathways. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The obtained results show that hydrogen-rich water significantly increased the levels of superoxide dismutase and structural proteins; activated the Nrf-2 signaling pathway; downregulated the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen is comparable to sulfasalazine as a treatment for DSS-induced colitis in mice.
This animal study examined Molecular hydrogen is comparable to sulfasalazine as a treatment for DSS-induced colitis in mice. The abstract describes Mouse model; sample size 6; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreRecent advances in studies of molecular hydrogen in the treatment of pancreatitis.
Pancreatitis is an inflammatory disease of the pancreas characterized by acinar cell injury and is associated with the abnormal release of trypsin, which results in high mortality due to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS). The inflammatory response, impaired autophagic flux, endoplasmic reticulum stress (ERS) and their interactions are involved in the development of pancreatitis. Molecular hydrogen (H) is a novel antioxidant that possesses the features of selective scavenging of oxygen free radicals and nontoxic metabolites and has been shown to be efficacious for treating…
Read MoreProtective Effects of Hydrogen Gas on Experimental Acute Pancreatitis.
This uncontrolled human study examined Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis. The abstract describes Human participants. The abstract reports: The results revealed significant reductions in inflammation and oxidative stress both in vitro and in vivo. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreSirtuin Type 1 Mediates the Retinal Protective Effect of Hydrogen-Rich Saline Against Light-Induced Damage in Rats.
This animal study examined Sirtuin Type 1 Mediates the Retinal Protective Effect of Hydrogen-Rich Saline Against Light-Induced Damage in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 5 days. The abstract reports: Sirt1 mediates light-induced damage mitigation by HRS through inhibition of apoptosis and oxidant-stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats.
This animal study examined The effect of Hydrogen-rich water on retinal degeneration in the outer nuclear layer of simulated weightlessness rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Oxidative stress has been identified as one of the contributing mechanisms of spaceflight-associated neuro-ocular syndrome (SANS), and hydrogen (H) has demonstrated significant antioxidant and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemia/reperfusion injury through the PI3K/Akt pathway.
This animal study examined Hydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemia/reperfusion injury through the PI3K/Akt pathway. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: The results showed that administration of HPC significantly inhibited the apoptosis of RGCs and protected the visual function. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDrinking hydrogen water improves photoreceptor structure and function in retinal degeneration 6 mice.
This animal study examined Drinking hydrogen water improves photoreceptor structure and function in retinal degeneration 6 mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Given the known contributions of oxidative stress caused by reactive oxygen species (ROS) and selective inhibition of potent ROS peroxynitrite and OH·by H gas…. This is an automated editorial draft based on the abstract and requires source review before publication.
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