Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus.
This preclinical study evaluated hydrogen gas in rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
Read MoreHydrogen activates ACOD1-itaconate pathway to ameliorate steroid-associated osteonecrosis.
In mice, HRW-treated mice exhibit improved serum lipid profiles, including decreased levels of low-density lipoprotein (LDL), triglycerides (TG), and total cholesterol (T-CHO), as well as reduced lipid accumulation. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
Read MoreEffects of hydrogen water treatment on antioxidant system of litchi fruit during the pericarp browning.
Compared with control pericarp, the pericarp of HW-treated litchi fruit exhibited higher levels of superoxide radical (O₂-·) scavenging activity, glutathione (GSH), monodehydroascorbate reductase (MDHAR), polyphenol oxidase (PPO) and total flavonoids during whole storage, higher levels of hydrogen peroxide (H₂O₂), catalase (CAT), glutathione disulfide (GSSG), ascorbate oxidase (AAO) and total phenols only on day 1. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record. This plant postharvest study evaluated hydrogen water and is included as Related Mechanisms & Background Science. It provides no evidence of therapeutic effectiveness in humans or animals.
Read MoreHydration Mechanism of the Hydrogen-Rich Water Based Cement Paste
This study examined Hydration Mechanism of the Hydrogen-Rich Water Based Cement Paste. The abstract describes hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-related enhancement of in vivo antioxidant ability in the brain of rats fed coral calcium hydride.
This animal study examined Hydrogen-related enhancement of in vivo antioxidant ability in the brain of rats fed coral calcium hydride. The abstract describes Rat model; reported duration 4 weeks. The abstract reports: These results clarify the mechanism that CCH may exert antioxidant activity by significantly enhancing the basal endogenous antioxidant ability in the hippocampus through a…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes.
HW-bathing significantly improved wrinkle in four subjects on the back of neck on 90th day as compared to 0 day. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.
Read MoreDependencies of hydrogen-water on mineral-based hardness, temperatures and the container materials, and effects of the oral washing and drinking.
Drinking-pause for 4 weeks after drinking hydrogen-water, however, saliva ORP, gradually but not instantly, increased to +60 to +80 mV, but upon drinking-resumption and 2 weeks thereafter, decreased again to -100 to -110 mV, suggesting that several-week hydrogen-water drinking caused a certain decrease in the saliva ORP. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreAntioxidant activities of nano-bubble hydrogen-dissolved water assessed by ESR and 2,2′-bipyridyl methods.
Nano-bubble hydrogen water showed the strongest hydroxyl-radical scavenging activity among the water samples tested by electron-spin-resonance analysis. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreEnhancing tomato fruit antioxidant potential through hydrogen nanobubble irrigation.
Antioxidant concentrations of lycopene, ascorbic acid, flavonoids, and resveratrol in hydrogen nanobubble water drip-irrigated tomato fruits increased by 16.3-264.8% and 2.2-19.8%, respectively, compared to underground water and oxygen nanobubble water. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreAnti-diabetes effect of water containing hydrogen molecule and Pt nanoparticles.
In an animal model, electrochemically reduced water (ERW) contains a lot of hydrogen molecule (H₂ ) and scavenges reactive oxygen species (ROS) to protect DNA from oxidative damage. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
Read MoreMagnesium metal–a potential biomaterial with antibone cancer properties.
In a laboratory model, it is found that the H₂ released from the Mg degradation could scavenge free radicals both in the Fenton Reaction system and bone cancer cells. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.
Read MoreNitric oxide is involved in hydrogen gas-induced cell cycle activation during adventitious root formation in cucumber.
HRW treatment increased NO content in a time-dependent fashion. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
Read MoreNeuroprotective effects of hydrogen saline in neonatal hypoxia-ischemia rat model.
The researchers observed that H(2) saline treatment reduced the caspase activity, MDA, Iba-1 levels, the infarct ratio, and improved the long-term neurological and neurobehavioral functions. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
Read MoreProtective effect of hydrogen-rich saline on decompression sickness in rats.
Hydrogen-rich saline reduced decompression-sickness incidence and associated lung and spinal-cord injury markers in rats. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
Read MoreHydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway.
In the CPB group without the hydrogen-rich saline treatment, the expression levels of B-cell lymphoma (Bcl)-2, JAK2, phospho-JAK2 (p-JAK2), STAT3 and phospho-STAT3 (p-STAT3) were significantly decreased, and Bax was significantly increased, compared with the Sham group. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
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