Preconditioning with one-time hydrogen gas does not attenuate skin flap ischemia-reperfusion injury in rat models.

This animal study examined Preconditioning with one-time hydrogen gas does not attenuate skin flap ischemia-reperfusion injury in rat models. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Preconditioning with one-time inhaled hydrogen does not attenuate skin flap IR injuries in rat models. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model.

This animal study examined Hydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results of this study support the hypothesis that oral administration of hydrogen-rich water benefits the wound healing process by decreasing oxidative stress and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC/Nga Mice.

This animal study examined The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC/Nga Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 25 days. The abstract reports: The results suggest that HW affects allergic contact dermatitis through modulation of Th1 and Th2 responses in NC/Nga mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Positive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice.

This animal study examined Positive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: In the present study, we investigated the effect of drinking hydrogen water (HW) on 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis in NC/Nga mice and found that…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice.

This animal study examined Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice. The abstract describes Mouse model; sample size 11; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: Levels of serum thymus and activation-regulated chemokine (TARC) and cytokines in the AD lesion were measured by ELISA; and mRNA expression of TARC  and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water ameliorates imiquimod-induced psoriasis-like skin lesions and regulates macrophage polarization in dyslipidemic ApoE-deficient mice.

This animal study examined Hydrogen-rich water ameliorates imiquimod-induced psoriasis-like skin lesions and regulates macrophage polarization in dyslipidemic ApoE-deficient mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: The results revealed that HRW significantly reduced plasma triglyceride and total cholesterol levels, increased high-density lipoprotein cholesterol levels, and alleviated skin lesions in mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect and mechanism of hydrogen‐rich bath on mice with imiquimod‐induced psoriasis

This animal study examined Effect and mechanism of hydrogen‐rich bath on mice with imiquimod‐induced psoriasis. The abstract describes Mouse model; hydrogen delivered as hydrogen water and hydrogen bath and topical hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats.

This animal study examined Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats. The abstract describes Rat model. The abstract reports: The Si-based agent suppressed oxidative stress, apoptosis, and inflammatory reactions resulting from I/R injury, thereby contributing to improvements in skin flap survival. This is an automated editorial draft based on the abstract and requires source review before publication.

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Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model.

This animal study examined Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 5 min. The abstract reports: Many studies have demonstrated the therapeutic effects of hydrogen in pathological conditions such as inflammation; however, little is known about its prophylactic effects. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline reduces tissue injury and improves skin flap survival on a rat hindlimb degloving injury model.

This animal study examined Hydrogen-rich saline reduces tissue injury and improves skin flap survival on a rat hindlimb degloving injury model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 5 days. The abstract reports: Repeated HRS injections after trauma increased the viability of skin flap in rat degloving injury model by decreasing local tissue injury, due to its…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen Gas Protects Against Intestinal Injury in Wild Type But Not NRF2 Knockout Mice With Severe Sepsis by Regulating HO-1 and HMGB1 Release.

This animal study examined Hydrogen Gas Protects Against Intestinal Injury in Wild Type But Not NRF2 Knockout Mice With Severe Sepsis by Regulating HO-1 and HMGB1 Release. The abstract describes Mouse model. The abstract reports: The results showed that therapy with 2% H2 increased the survival rate, alleviated the injuries caused by oxidative stress and inflammation, reduced HMGB1 levels…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota.

This uncontrolled human study examined Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota. The abstract describes Human participants; hydrogen delivered as hydrogen water and hydrogen inhalation. The abstract reports: Molecular hydrogen treatment promotes functional outcomes after SAE in mice, which may be attributable to increasing beneficial bacteria, repressing harmful bacteria, and metabolic disorder,…. This is an automated editorial draft based on the abstract and requires source review before publication.

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High-concentration hydrogen inhalation mitigates sepsis-associated encephalopathy in mice by improving mitochondrial dynamics.

This animal study examined High-concentration hydrogen inhalation mitigates sepsis-associated encephalopathy in mice by improving mitochondrial dynamics. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: Inhalation of high concentration (67%) of H in septic mice improved the survival rate and reduced neuronal injury. Its mechanism might be mediated by…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen‐rich and hyperoxygenate saline inhibits lipopolysaccharide‐induced lung injury through mediating NF‐κB/NLRP3 signaling pathway in C57BL/6 mice

This animal study examined Hydrogen‐rich and hyperoxygenate saline inhibits lipopolysaccharide‐induced lung injury through mediating NF‐κB/NLRP3 signaling pathway in C57BL/6 mice. The abstract describes Mouse model; hydrogen delivered as injected or infused hydrogen. The abstract reports: Hydrogen plays a more important role in the inflammatory and anti-apoptosis mechanisms, while oxygen improves hypoxia of the body, and thus, its molecular mechanism…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Safety of inhaled hydrogen gas in healthy mice.

This animal study examined Safety of inhaled hydrogen gas in healthy mice. The abstract describes Mouse model; sample size 25; hydrogen delivered as hydrogen inhalation; reported duration 72 hours. This is an automated editorial draft based on the abstract and requires source review before publication.

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