Intake of water with high levels of dissolved hydrogen (H2) suppresses ischemia-induced cardio-renal injury in Dahl salt-sensitive rats.
This animal study examined Intake of water with high levels of dissolved hydrogen (H2) suppresses ischemia-induced cardio-renal injury in Dahl salt-sensitive rats. The abstract describes Rat model. The abstract reports: Consumption of EW by ad libitum drinking has the potential to ameliorate ischemia-induced cardio-renal injury in CKD model rats. This indicates a novel strategy…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline ameliorated LPS-induced acute lung injury via autophagy inhibition through the ROS/AMPK/mTOR pathway in mice.
This animal study examined Hydrogen-rich saline ameliorated LPS-induced acute lung injury via autophagy inhibition through the ROS/AMPK/mTOR pathway in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results showed that HRS ameliorated lipopolysaccharide-induced ALI in mice by inhibiting autophagy over-activation through ROS/AMPK/mTOR pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreAnti-obesity effect of alkaline reduced water in high fat-fed obese mice.
This animal study examined Anti-obesity effect of alkaline reduced water in high fat-fed obese mice. The abstract describes Mouse model; reported duration 12 weeks. The abstract reports: We found that ARW-fed mice significantly ameliorated adiposity: controlled body weight gain, reduced the accumulation of epididymal fats and decreased liver fats as compared…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePectin and high-amylose maize starch increase caecal hydrogen production and relieve hepatic ischaemia-reperfusion injury in rats.
This animal study examined Pectin and high-amylose maize starch increase caecal hydrogen production and relieve hepatic ischaemia-reperfusion injury in rats. The abstract describes Rat model. The abstract reports: We investigated whether the feeding of high H2-generating dietary fibre and resistant starch (RS) could suppress hepatic ischaemia-reperfusion (IR) injury, which results from oxidative…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNew Treatment for the Cognitive and Emotional Deficits Linked with Paclitaxel-Induced Peripheral Neuropathy in Mice.
This uncontrolled human study examined New Treatment for the Cognitive and Emotional Deficits Linked with Paclitaxel-Induced Peripheral Neuropathy in Mice. The abstract describes Human participants; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The results revealed: (1) the antiallodynic actions of HRW administered at one or two times per day during 7 and 3 consecutive days; (2)…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective Effects of Different Kinds of Filtered Water on Hypertensive Mouse by Suppressing Oxidative Stress and Inflammation.
This uncontrolled human study examined Protective Effects of Different Kinds of Filtered Water on Hypertensive Mouse by Suppressing Oxidative Stress and Inflammation. The abstract describes Human participants; reported duration 1 month. The abstract reports: The results demonstrated that filtered water can reduce the blood pressure. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines.
This animal study examined Protective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Here, we found that HS treatment significantly reduced infarct volume and improved neurobehavioral outcomes at 24h, 48h and 72h after pMCAO operation in a…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreLactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression.
This animal study examined Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression. The abstract describes Rat model. The abstract reports: Behaviorally, rats in the lactulose administration group won higher neurological scores and showed shorter escape latency time in the Morris test. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHyperbaric Oxygen Combined With Hydrogen-rich Saline Protect Against Acute Lung Injury Induced by Lipopolysaccharide in Rat Model
This animal study examined Hyperbaric Oxygen Combined With Hydrogen-rich Saline Protect Against Acute Lung Injury Induced by Lipopolysaccharide in Rat Model. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Results: In the groups treated with HRS and HBO, pulmonary pathological data, wet-dry weight ratio and immflammatory factors in the pulmonary tissues and avelar…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of hydrogen-rich saline on rats with acute carbon monoxide poisoning.
This animal study examined Effects of hydrogen-rich saline on rats with acute carbon monoxide poisoning. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: H(2)-rich saline may effectively protect the brain from injury after acute CO poisoning. The mechanism of this protection may be related to lessening oxidative…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages.
This animal study examined Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 42 days. The abstract reports: Hydrogen inhalation (75%) ameliorated SCI in vivo and attenuated neuronal mechanical injuries in vitro, and its protective effect on spinal cord neurons was exerted…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis.
This animal study examined Inhalation of hydrogen gas attenuates brain injury in mice with cecal ligation and puncture via inhibiting neuroinflammation, oxidative stress and neuronal apoptosis. The abstract describes Mouse model; reported duration 60 min. The abstract reports: CLP mice showed obvious brain injury characterized by aggravated pathological damage, BBB disruption and brain edema at 24h after CLP operation, which was markedly…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway.
This uncontrolled human study examined Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway. The abstract describes Human participants. The abstract reports: The results of MTT indicated that H2 and RAP could increase cell viability after OGD/R treatment, while 3-MA further aggravated injury and inhibited the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of molecular hydrogen on hepatotoxicity induced by sub-chronic exposure to chlorpyrifos in rats.
This animal study examined Protective effects of molecular hydrogen on hepatotoxicity induced by sub-chronic exposure to chlorpyrifos in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water; reported duration 8 weeks. The abstract reports: The results obtained suggest that HRW intake can protect rats from CPF induced hepatotoxicity, and the oxidative stress signaling and the mitochondrial pathway may…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDrinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson’s disease in rats.
This uncontrolled human study examined Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkinson’s disease in rats. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Lack of dose responses of hydrogen and the presence of favorable effects with hydrogen water and intermittent hydrogen gas suggest that signal modulating activities…. This is an automated editorial draft based on the abstract and requires source review before publication.
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