[The protection of hydrogen-rich saline on a rat dry eye model induced by scopolamine hydrobromide].

This animal study examined [The protection of hydrogen-rich saline on a rat dry eye model induced by scopolamine hydrobromide]. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The difference of SIt, BUT and fluorescein staining score between the groups was statistically significant on the 14th day(5.194, 3.894, 16.487, 0.05), the values…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effects of hydrogen rich water on the expression of Nrf 2 and the oxidative stress in rats with traumatic brain injury].

This animal study examined [Effects of hydrogen rich water on the expression of Nrf 2 and the oxidative stress in rats with traumatic brain injury]. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 5 days. The abstract reports: Compared with TBI group, the parameters in HW group were improved, and they were similar as sham operation group. (3) RT-qPCR: no significant difference…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Role of FOXO3a in process of hydrogen-rich saline attenuating global cerebral ischemia-reperfusion injury in rats].

This animal study examined [Role of FOXO3a in process of hydrogen-rich saline attenuating global cerebral ischemia-reperfusion injury in rats]. The abstract describes Rat model; sample size 12; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline can attenuate global cerebral I/R injure through inhibiting JNK, reducing the expression of FOXO3a. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion in rats].

This animal study examined [Effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion in rats]. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline can reduce myocardial reperfusion injury and improve heart function. The mechanism may be due to associated with the down-regulated expressions of Akt…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effects of hydrogen-rich saline on endoplasmic reticulum stress during myocardial ischemia-reperfusion in rats].

This animal study examined [Effects of hydrogen-rich saline on endoplasmic reticulum stress during myocardial ischemia-reperfusion in rats]. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 30 min. The abstract reports: Hydrogen-rich saline may decrease cell apoptosis and attenuate myocardial reperfusion injury through inhibiting endoplasmic reticulum stress. The mechanism may be associated with decreasing the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Protective effects of inhaled hydrogen gas on cognitive function in mice with sepsis-associated encephalopathy].

This animal study examined [Protective effects of inhaled hydrogen gas on cognitive function in mice with sepsis-associated encephalopathy]. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.

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[The role of Nrf2 in the hydrogen treatment for intestinal injury caused by severe sepsis].

This animal study examined [The role of Nrf2 in the hydrogen treatment for intestinal injury caused by severe sepsis]. The abstract describes Mouse model; sample size 38. The abstract reports: Through activation of Nrf2-antioxidant response element (ARE) pathway, hydrogen may increase the level of Nrf2, which is a kind of protective protein, in the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effects of hydrogen inhalation on serum pro-inflammatory factors and intestinal injury in mice with severe sepsis].

This animal study examined [Effects of hydrogen inhalation on serum pro-inflammatory factors and intestinal injury in mice with severe sepsis]. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. The abstract reports: Hydrogen inhalation can down-regulate the systemic inflammatory response to ameliorate the intestinal injury, and it may improve the septic process and increase the survival…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effect of combination therapy with propofol and hydrogen-rich saline on organ damage and cytokines in a murine model of sepsis].

This animal study examined [Effect of combination therapy with propofol and hydrogen-rich saline on organ damage and cytokines in a murine model of sepsis]. The abstract describes Mouse model; sample size 28; hydrogen delivered as hydrogen-rich saline; reported duration 7 days. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Suppression of experimental abdominal aortic aneurysm by saturated hydrogen saline: a preliminary study with rats].

This animal study examined [Suppression of experimental abdominal aortic aneurysm by saturated hydrogen saline: a preliminary study with rats]. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Role of hydrogen gas in regulating of poly (ADP-ribose) polymerase-1 dependent cell death in rat Schwann cells].

This animal study examined [Role of hydrogen gas in regulating of poly (ADP-ribose) polymerase-1 dependent cell death in rat Schwann cells]. The abstract describes Rat model; reported duration 48 hours. The abstract reports: A small amount of AIF expression was found in the nucleus of HG+H2 group, which indicated that high glucose could promote the AIF nuclear…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Different types of molecular hydrogen donors and their pharmacokinetics in vivo].

This animal study examined [Different types of molecular hydrogen donors and their pharmacokinetics in vivo]. The abstract describes Animal model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.

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Pretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats.

This animal study examined Pretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Pretreatment by HRS ameliorated renal dysfunction in glycerol-induced rhabdomyolysis by inhibiting oxidative stress and the inflammatory response. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney.

This uncontrolled human study examined Hydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: These results indicate that HRW inhibits the production of α,β-dicarbonyl compounds and ROS in the kidneys of SHR.Cg-Leprcp/NDmcr rats. Therefore, it has therapeutic potential…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich medium suppresses the generation of reactive oxygen species, elevates the Bcl-2/Bax ratio and inhibits advanced glycation end product-induced apoptosis.

This in vitro or cellular study examined Hydrogen-rich medium suppresses the generation of reactive oxygen species, elevates the Bcl-2/Bax ratio and inhibits advanced glycation end product-induced apoptosis. The abstract describes Endothelial cell model. This is an automated editorial draft based on the abstract and requires source review before publication.

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