Hydrogen therapy after resuscitation improves myocardial injury involving inhibition of autophagy in an asphyxial rat model of cardiac arrest
This animal study examined Hydrogen therapy after resuscitation improves myocardial injury involving inhibition of autophagy in an asphyxial rat model of cardiac arrest. The abstract describes Rat model. The abstract reports: The results showed that H therapy significantly improved post-resuscitation survival and cardiac function. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen alleviates lung injury after traumatic brain injury: Pyroptosis and apoptosis.
This uncontrolled human study examined Molecular hydrogen alleviates lung injury after traumatic brain injury: Pyroptosis and apoptosis. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: H improves TBI-ALI, and the mechanism may be due to the decrease of both pyroptosis and apoptosis and the alleviation of inflammation. These findings…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreIntravenous Hydrogen Therapy With Intracisternal Magnesium Sulfate Infusion in Severe Aneurysmal Subarachnoid Hemorrhage
Poor-grade subarachnoid hemorrhage still has a poor prognosis. This randomized controlled clinical trial evaluated intracisternal magnesium sulfate infusion combined with intravenous hydrogen therapy in patients with poor-grade subarachnoid hemorrhage. Thirty-seven patients with poor-grade subarachnoid hemorrhage were randomized to Mg+H, Mg, and control groups.
Read MoreHydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury
This animal study examined Hydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Recent studies have demonstrated the potential neuroprotective effects of molecular hydrogen on TBI. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of a high concentration of hydrogen on neurological function after traumatic brain injury in diabetic rats.
This uncontrolled human study examined Effects of a high concentration of hydrogen on neurological function after traumatic brain injury in diabetic rats. The abstract describes Human participants. The abstract reports: We found that the inhalation of high concentrations of H significantly improved outcomes following TBI in diabetic rats. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest
This animal study examined Inhalation of high-concentration hydrogen gas attenuates cognitive deficits in a rat model of asphyxia induced-cardiac arrest. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. The abstract reports: Our findings suggest that water electrolysis derived 67% hydrogen gas may be an effective therapeutic approach for improving cognitive outcomes associated with global brain…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline ameliorates hippocampal neuron apoptosis through up-regulating the expression of cystathionine β-synthase (CBS) after cerebral ischemia- reperfusion in rats.
This animal study examined Hydrogen-rich saline ameliorates hippocampal neuron apoptosis through up-regulating the expression of cystathionine β-synthase (CBS) after cerebral ischemia- reperfusion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 2 hr. The abstract reports: This study showed that hydrogen-rich saline ameliorates cell injury through up-regulating the expression of CBS in the hippocampus after cerebral ischemia reperfusion (I/R) in…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway.
This animal study examined Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: Our results indicate that hydrogen-rich water has neuroprotective effects against TBI by reducing oxidative stress and activating the Nrf2 pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3β signaling pathway.
This in vitro or cellular study examined Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3β signaling pathway. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HS could attenuate neuronal apoptosis in EBI and improve the neurofunctional outcome after SAH, partially via the Akt/GSK3β pathway. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits.
This animal study examined Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits. The abstract describes Rabbit model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results suggest that treatment with hydrogen in experimental SAH rabbits could alleviate brain injury via decreasing the oxidative stress injury and brain edema.…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis.
This animal study examined Hydrogen inhalation improves mouse neurological outcomes after cerebral ischemia/reperfusion independent of anti-necroptosis. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline injection into the subarachnoid cavity within 2 weeks promotes recovery after acute spinal cord injury.
This animal study examined Hydrogen-rich saline injection into the subarachnoid cavity within 2 weeks promotes recovery after acute spinal cord injury. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 2 weeks. The abstract reports: Results at 24 hours, 48 hours, 1 week and 2 weeks after injury showed that hydrogen-rich saline markedly reduced cell death, inflammatory cell infiltration,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome.
This uncontrolled human study examined Hydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen saline suppresses neuronal cell apoptosis and inhibits the p38 mitogen‑activated protein kinase‑caspase‑3 signaling pathway following cerebral ischemia‑reperfusion injury.
This animal study examined Hydrogen saline suppresses neuronal cell apoptosis and inhibits the p38 mitogen‑activated protein kinase‑caspase‑3 signaling pathway following cerebral ischemia‑reperfusion injury. The abstract describes Rat model; sample size 60; hydrogen delivered as hydrogen-rich saline. The abstract reports: These results demonstrated that H2 significantly reduced the number of apoptotic cells, and the protein expression of p38 MAPK and caspase‑3, compared with the…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen does not Exert Neuroprotective Effects or Improve Functional Outcomes in Rats After Intracerebral Hemorrhage.
This animal study examined Hydrogen does not Exert Neuroprotective Effects or Improve Functional Outcomes in Rats After Intracerebral Hemorrhage. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline; reported duration 3 days. The abstract reports: Hydrogen administration without surgery has no neuroprotective effect in the blood injection rat ICH model. This is an automated editorial draft based on the abstract and requires source review before publication.
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