Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury.
This animal study examined Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: We found that mHW reversed CCI-induced edema by about half, completely blocked pathological tau expression, accentuated an early increase seen in several cytokines but…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice.
This animal study examined Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice. The abstract describes Mouse model; sample size 1; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Activation of mast cells following intracerebral hemorrhage contributed to increase of blood-brain barrier permeability and brain edema. Hydrogen inhalation preserved blood-brain barrier disruption by…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model.
This animal study examined Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: H gas administration exerted a neuroprotective effect against early brain injury after ICH through anti-inflammatory, neuroprotective, anti-apoptotic, and antioxidative activity. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death.
This animal study examined Hydrogen gas inhalation during ex vivo lung perfusion of donor lungs recovered after cardiac death. The abstract describes Animal model; hydrogen delivered as hydrogen inhalation; reported duration 1 hour. The abstract reports: Hydrogen gas inhalation during EVLP improved donation after cardiac death lung function via reduction of inflammation and apoptosis, and this effect persisted after LTx. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreCombination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial.
This randomized controlled trial examined Combination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial. The abstract describes Human participants; sample size 39; hydrogen delivered as hydrogen inhalation. The abstract reports: The Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During Post-Cardiac Arrest Care (HYBRID) II trial (jRCTs031180352) suggested that hydrogen inhalation may…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats.
This uncontrolled human study examined Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Our results demonstrated that TBI-challenged rats exhibited significant brain injuries that were characterized by decreased survival rate and increased BBB permeability, brain edema, and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage.
This animal study examined Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: Our results suggest that hydrogen inhalation exerts an acute brain-protective effect in the mouse ICH model. However, the acute hydrogen therapy alone is not…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates hippocampus endoplasmic reticulum stress after cardiac arrest in rats
This animal study examined Hydrogen-rich saline attenuates hippocampus endoplasmic reticulum stress after cardiac arrest in rats. The abstract describes Rat model; sample size 30; hydrogen delivered as hydrogen-rich saline. The abstract reports: Hydrogen-rich saline attenuates brain I/R injury may through inhibiting hippocampus ERS after cardiac arrest in rats. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats.
This animal study examined Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats. The abstract describes Rat model; sample size 28; hydrogen delivered as hydrogen water. The abstract reports: The present study suggests that ingestion of HRW can improve neurological function outcome in the SHRSP model. This beneficial effect may be due to…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreNeuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression.
This animal study examined Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Recently, it has been suggested that molecular hydrogen (H) can selectively reduce the levels of hydroxyl radicals (.OH), and ameliorate oxidative and inflammatory injuries…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInfluence of oxygen concentration on the neuroprotective effect of hydrogen inhalation in a rat model of cardiac arrest
This uncontrolled human study examined Influence of oxygen concentration on the neuroprotective effect of hydrogen inhalation in a rat model of cardiac arrest. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation. The abstract reports: In this CA rat model, inhaling 2% hydrogen combined with a high concentration of oxygen improved 96-h survival, either under normothermia or under hypothermia. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury.
This uncontrolled human study examined Hydrogen-rich saline protects against oxidative damage and cognitive deficits after mild traumatic brain injury. The abstract describes Human participants; hydrogen delivered as hydrogen-rich saline. The abstract reports: Oxidative stress is the principal factor in traumatic brain injury (TBI) that initiates events that result in protracted neuronal dysfunction and remodeling. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage.
This in vitro or cellular study examined Hydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen inhalation. The abstract reports: CV showed no significant improvement between the control and H groups. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas attenuates cognitive impairment in transient cerebral ischemia via inhibition of oxidative stress.
This animal study examined Inhalation of hydrogen gas attenuates cognitive impairment in transient cerebral ischemia via inhibition of oxidative stress. The abstract describes Rat model; sample size 30; reported duration 3 hours. The abstract reports: Inhalation of hydrogen gas could attenuate cognitive impairment in the ischemic rats. This protection is associated with decreased neuronal death in CA1 region and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEfficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.
Hydrogen gas inhalation (HI) improved survival and neurological outcomes in an animal model of post-cardiac arrest syndrome (PCAS). The feasibility and safety of HI for patients with PCAS was confirmed in a pilot study. The objective of this study is to evaluate the efficacy of HI for patients with PCAS.
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