Hydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model.

This animal study examined Hydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: The results of this study support the hypothesis that oral administration of hydrogen-rich water benefits the wound healing process by decreasing oxidative stress and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment

This in vitro or cellular study examined Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts in culture or 3D-tissue equivalents, and wound-healing promotion, together with ROS-scavenging and relief from glutathione diminishment. The abstract describes Fibroblast model; hydrogen delivered as hydrogen water. The abstract reports: Extract from HW-treated HGF cells scavenged ROO· more markedly than that from DDW-treated cells, suggesting that HW can increase the intracellular antioxidant capacity. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC/Nga Mice.

This animal study examined The Drinking Effect of Hydrogen Water on Atopic Dermatitis Induced by Dermatophagoides farinae Allergen in NC/Nga Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 25 days. The abstract reports: The results suggest that HW affects allergic contact dermatitis through modulation of Th1 and Th2 responses in NC/Nga mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Positive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice.

This animal study examined Positive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: In the present study, we investigated the effect of drinking hydrogen water (HW) on 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis in NC/Nga mice and found that…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice.

This animal study examined Hydrogen water ameliorates the severity of atopic dermatitis-like lesions and decreases interleukin-1β, interleukin-33, and mast cell infiltration in NC/Nga mice. The abstract describes Mouse model; sample size 11; hydrogen delivered as hydrogen water; reported duration 4 weeks. The abstract reports: Levels of serum thymus and activation-regulated chemokine (TARC) and cytokines in the AD lesion were measured by ELISA; and mRNA expression of TARC  and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Repetitive Bathing and Skin Poultice with Hydrogen-Rich Water Improve Wrinkles and Blotches Together with Modulation of Skin Oiliness and Moisture

This uncontrolled human study examined Repetitive Bathing and Skin Poultice with Hydrogen-Rich Water Improve Wrinkles and Blotches Together with Modulation of Skin Oiliness and Moisture. The abstract describes Human participants; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: Daily 10 min HW (dissolved hydrogen: 338–682 μg/mL, 41 °C) bathing and skin poultice with HW-impregnated towels for 11–98 days were demonstrated to improve…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Topically Applied Molecular Hydrogen Normalizes Skin Parameters Associated with Oxidative Stress: A Pilot Study.

This uncontrolled human study examined Topically Applied Molecular Hydrogen Normalizes Skin Parameters Associated with Oxidative Stress: A Pilot Study. The abstract describes Human participants; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: Although porphyrin levels showed a trend toward reduction, this change was not statistically significant. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS–STING pathway

This animal study examined Hydrogen ameliorates psoriasis-like skin inflammation via inhibiting the cGAS–STING pathway | Clinical and Experimental Immunology | Oxford Academic. The abstract describes Mouse model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: In a previous study, we demonstrated in a psoriasis mouse model that hydrogen-rich water, an effective reactive oxygen species (ROS) scavenger, significantly improves disease…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Progress in the Application of Molecular Hydrogen in Medical Skin Cosmetology.

Molecular hydrogen is a colorless, tasteless, biologically active small-molecule gas with reducing properties, demonstrating therapeutic and preventive effects across various human systems. Its mechanisms of action include selective antioxidation, anti-inflammatory effects, apoptosis inhibition, and the regulation of gene expression and signaling pathways. In the skin, molecular hydrogen reduces oxidative damage by scavenging free radicals and inhibiting oxidative stress, leading to improvements in texture and tone.

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Hydrogen-rich water ameliorates imiquimod-induced psoriasis-like skin lesions and regulates macrophage polarization in dyslipidemic ApoE-deficient mice.

This animal study examined Hydrogen-rich water ameliorates imiquimod-induced psoriasis-like skin lesions and regulates macrophage polarization in dyslipidemic ApoE-deficient mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and topical hydrogen. The abstract reports: The results revealed that HRW significantly reduced plasma triglyceride and total cholesterol levels, increased high-density lipoprotein cholesterol levels, and alleviated skin lesions in mice. This is an automated editorial draft based on the abstract and requires source review before publication.

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Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress.

This animal study examined Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress. The abstract describes Mouse model. The abstract reports: Our findings support the notion that long-term, intermittent environmental exposure to hydrogen gas in daily life has a beneficial effect on UVA-induced photoaging. Geriatr…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Combined use of hydrogen-rich water and enzyme-digested edible bird’s nest improves PMA/LPS-impaired wound healing in human inflammatory gingival tissue equivalents

This in vitro or cellular study examined Combined use of hydrogen-rich water and enzyme-digested edible bird’s nest improves PMA/LPS-impaired wound healing in human inflammatory gingival tissue equivalents. The abstract describes Keratinocyte model; hydrogen delivered as hydrogen water. The abstract reports: Remarkably, the combined use of HW and EBND exhibited particularly robust results. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect and mechanism of hydrogen‐rich bath on mice with imiquimod‐induced psoriasis

This animal study examined Effect and mechanism of hydrogen‐rich bath on mice with imiquimod‐induced psoriasis. The abstract describes Mouse model; hydrogen delivered as hydrogen water and hydrogen bath and topical hydrogen. This is an automated editorial draft based on the abstract and requires source review before publication.

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Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway.

This animal study examined Local Treatment of Hydrogen-Rich Saline Promotes Wound Healing In Vivo by Inhibiting Oxidative Stress via Nrf-2/HO-1 Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that local treatment of hydrogen-rich saline shortened wound closure time and reduced the level of proinflammatory cytokines and lipid peroxidation. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats.

This animal study examined Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats. The abstract describes Rat model. The abstract reports: The Si-based agent suppressed oxidative stress, apoptosis, and inflammatory reactions resulting from I/R injury, thereby contributing to improvements in skin flap survival. This is an automated editorial draft based on the abstract and requires source review before publication.

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