Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice.
This animal study examined Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen; reported duration 3 days. The abstract reports: We found that HRS administration significantly reduced body weight loss, jumping behavior and wet-dog shakes in mice underwent naloxone-precipitated withdrawal, and attenuated anxiety-like behaviors…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreEffects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder.
This animal study examined Effects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder. The abstract describes Animal model. The abstract reports: Our results showed that increased SDS and SAS indices and decreased alpha diversity indicated more serious mental disorders and lower bacterial diversity in METH…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Regulates Microglial Phagocytosis and Restores Behavioral Deficits Following Hypoxia-Ischemia Injury in Neonatal Mice via the Akt Pathway.
This animal study examined Hydrogen-Rich Saline Regulates Microglial Phagocytosis and Restores Behavioral Deficits Following Hypoxia-Ischemia Injury in Neonatal Mice via the Akt Pathway. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The result showed that HS administration alleviated HI-induced edema, infract volume and cellular apoptosis within the cortex of neonatal mice. Accompanying these indices of…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTreatment with Hydrogen-Rich Water Improves the Nociceptive and Anxio-Depressive-like Behaviors Associated with Chronic Inflammatory Pain in Mice.
This animal study examined Treatment with Hydrogen-Rich Water Improves the Nociceptive and Anxio-Depressive-like Behaviors Associated with Chronic Inflammatory Pain in Mice. The abstract describes Mouse model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: The potential use of molecular hydrogen (H) as a new therapy for neurological disorders has been demonstrated. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreProtective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats
This animal study examined Protective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats. The abstract describes Rat model; hydrogen delivered as hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MorePreadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury.
This animal study examined Preadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury. The abstract describes Mouse model; hydrogen delivered as hydrogen water; reported duration 3 days. The abstract reports: These results indicate the therapeutic potential of HW in preventing acute injury of the liver with attenuation of an increase in oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression
This animal study examined Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression. The abstract describes Mouse model. The abstract reports: The MCDHF I/R group showed higher levels of AST and ALT in serum, TUNEL-positive apoptotic cells, F4/80 immunopositive cells, mRNA levels of inflammatory cytokines,…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHypothermic Machine Perfusion with Hydrogen Gas Reduces Focal Injury in Rat Livers but Fails to Restore Organ Function.
This animal study examined Hypothermic Machine Perfusion with Hydrogen Gas Reduces Focal Injury in Rat Livers but Fails to Restore Organ Function. The abstract describes Rat model; reported duration 3 hours. The abstract reports: In conclusion, HMP and H gas treatment are partly effective in DCD rat livers but insufficient. Hypothermic machine perfusion can improve focal microcirculation and…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreInhalation of hydrogen gas reduces liver injury during major hepatotectomy in swine.
This animal study examined Inhalation of hydrogen gas reduces liver injury during major hepatotectomy in swine. The abstract describes Porcine model; sample size 14; reported duration 20 min. The abstract reports: H2 gas attenuates markedly ischemia and portal hyperperfusion injury in pigs with massive hepatotectomy, possibly by the reduction of inflammation and oxidative stress, maybe…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease: a randomized controlled pilot trial.
While non-alcoholic fatty liver disease (NAFLD) is rapidly becoming the most common liver disease worldwide, its treatment remains elusive. Since metabolic impairment plays a major role in NAFLD pathogenesis, any pharmaceuticals, such as molecular hydrogen (H), that advance lipid and glucose metabolism could be appropriate to tackle this complex condition. The aim of this study was to analyze the effects of 28-day hydrogen-rich water intake on liver fat deposition, body composition and lab chemistry profiles in overweight patients suffering from mild-to-moderate NAFLD.
Read MoreHydrogen-rich saline attenuates postoperative liver failure after major hepatectomy in rats.
This animal study examined Hydrogen-rich saline attenuates postoperative liver failure after major hepatectomy in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HS attenuates the massive hepatectomy induced liver injury not only by attenuating oxidative damage, but also by reducing the production of inflammatory cytokines, such…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-Rich Saline Attenuates Acute Kidney Injury After Liver Transplantation via Activating p53-Mediated Autophagy.
This animal study examined Hydrogen-Rich Saline Attenuates Acute Kidney Injury After Liver Transplantation via Activating p53-Mediated Autophagy. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: HRS is able to protect against AKI after liver transplantation partly by reducing apoptosis, which is possibly involved in the modulation of p53-mediated autophagy. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreDelivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications
This narrative review examined Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Flush After Cold Storage as a New End-Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury.
Cold storage (CS) remains the gold standard for organ preservation worldwide, although it is inevitably associated with ischemia/reperfusion injury (IRI). Molecular hydrogen (H ) is well known to have antioxidative properties. However, its unfavorable features, ie, inflammability, low solubility, and high tissue/substance permeability, have hampered its clinical application.
Read MoreThe Effect of Adjuvant Therapy with Molecular Hydrogen on Endogenous Coenzyme Q Levels and Platelet Mitochondrial Bioenergetics in Patients with Non-Alcoholic Fatty Liver Disease.
This uncontrolled human study examined The Effect of Adjuvant Therapy with Molecular Hydrogen on Endogenous Coenzyme Q Levels and Platelet Mitochondrial Bioenergetics in Patients with Non-Alcoholic Fatty Liver Disease. The abstract describes Human participants; sample size 30; hydrogen delivered as hydrogen water; reported duration 8 weeks. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreBlog Categories
Recent Posts
October 21, 2020
November 16, 2020
October 02, 2017