Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms.

This randomized controlled trial examined Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms. The abstract describes Human participants. The abstract reports: And for the patients with gastrointestinal symptoms, drinking AEW has been found to be effective in relieving gastrointestinal symptoms. This is an automated editorial draft based on the abstract and requires source review before publication.

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Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle.

This animal study examined Effect of molecular hydrogen saturated alkaline electrolyzed water on disuse muscle atrophy in gastrocnemius muscle. The abstract describes Rat model; reported duration 3 weeks. The abstract reports: We showed that 8-OHdG, but not MDA, significantly increased by 149% and 145% in HU-NW and HU-AEW, respectively, when compared with CONT. This is an automated editorial draft based on the abstract and requires source review before publication.

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MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline.

This animal study examined MicroRNA files in the prevention of intestinal ischemia/reperfusion injury by hydrogen rich saline. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Collectively, miR-199a-3p may serve a key role in the anti-apoptotic mechanism of HRS that contributes to its protection of the intestine against I/R injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen suppresses gut inflammation and pyroptosis in ulcerative colitis through promoting PKM2 lactylation to block NLRP3 inflammasome activation.

This uncontrolled human study examined Molecular hydrogen suppresses gut inflammation and pyroptosis in ulcerative colitis through promoting PKM2 lactylation to block NLRP3 inflammasome activation. The abstract describes Human participants; hydrogen delivered as hydrogen water. The abstract reports: Molecular hydrogen can promote PKM2 lactylation to restrain NLRP3 inflammasome-mediated pyroptosis and inflammation, thus ameliorating UC progression. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhaled hydrogen ameliorates endotoxin-induced bowel dysfunction.

This uncontrolled human study examined Inhaled hydrogen ameliorates endotoxin-induced bowel dysfunction. The abstract describes Human participants; hydrogen delivered as hydrogen inhalation and injected or infused hydrogen. The abstract reports: This study showed the protective effects of hydrogen inhalation on LPS-induced septic ileus through inhibition of inflammation in the muscularis propria. These inhibitory effects…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Recent advances in studies of molecular hydrogen in the treatment of pancreatitis.

This narrative review examined Recent advances in studies of molecular hydrogen in the treatment of pancreatitis. The abstract describes Published literature review. The abstract reports: Pancreatitis is an inflammatory disease of the pancreas characterized by acinar cell injury and is associated with the abnormal release of trypsin, which results…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis.

This uncontrolled human study examined Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis. The abstract describes Human participants. The abstract reports: The results revealed significant reductions in inflammation and oxidative stress both in vitro and in vivo. This is an automated editorial draft based on the abstract and requires source review before publication.

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Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence.

This animal study examined Sirt3 mediates the protective effect of hydrogen in inhibiting ROS-induced retinal senescence. The abstract describes Mouse model. The abstract reports: Moreover, this result was consistent with the downregulation of expression of the oxidative stress hallmark OGG1. This is an automated editorial draft based on the abstract and requires source review before publication.

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An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress

This in vitro or cellular study examined An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress. The abstract describes Epithelial cell model. The abstract reports: The results obtained with immunohistochemistry and pachymetry showed that in the corneas of H-pretreated eyes, slight oxidative stress appeared followed by an increased expression…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig.

This in vitro or cellular study examined Hydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: This result likely occurs by inhibiting the activation of glial cells, decreasing the production of the iNOS and GRP78 and promoting glutamate clearance. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury.

This animal study examined Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury. The abstract describes Rat model; reported duration 60 minutes. The abstract reports: H(2) has no known toxic effects on the human body. Thus, the results suggest that H(2)-loaded eye drops are a highly useful neuroprotective and…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells.

This in vitro or cellular study examined Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells. The abstract describes Cell culture / in vitro model. The abstract reports: The results in the present study indicate that miR-9, miR-199 and miR-21 play an important role in the anti-inflammatory regulation of LPS-activated microglia cells…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The preventive and therapeutic effects of molecular hydrogen in ocular diseases and injuries where oxidative stress is involved

This narrative review examined The preventive and therapeutic effects of molecular hydrogen in ocular diseases and injuries where oxidative stress is involved. The abstract describes Published literature review. The abstract reports: In this review, we present the results of studies utilising H in the treatment of ocular diseases involving oxidative stress. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Comparative Efficiency of Intraperitoneal and Intravitreous Injection of Hydrogen Rich Saline against -Methyl–Nitrosourea Induced Retinal Degeneration: A Topographic Study.

This animal study examined The Comparative Efficiency of Intraperitoneal and Intravitreous Injection of Hydrogen Rich Saline against -Methyl–Nitrosourea Induced Retinal Degeneration: A Topographic Study. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Particularly, the topographic measurements suggested that the IV delivery of HRS could alleviate MNU induced photoreceptor degeneration in the posterior retina. This is an automated editorial draft based on the abstract and requires source review before publication.

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Therapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage.

This animal study examined Therapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage. The abstract describes Rabbit model. The abstract reports: We previously found that UVB irradiation of the cornea caused the imbalance between the antioxidant and prooxidant enzymes in the corneal epithelium, followed by…. This is an automated editorial draft based on the abstract and requires source review before publication.

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