Hydrogen gas protects against ovariectomy-induced osteoporosis by inhibiting NF-κB activation.
This animal study examined Hydrogen gas protects against ovariectomy-induced osteoporosis by inhibiting NF-κB activation. The abstract describes Mouse model. The abstract reports: H2 markedly inhibited RANKL-induced activation, nuclear translocation, and transcriptional activity of NF-κB (P These results demonstrated that H2 could be an effective therapeutic agent…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreTreatment with hydrogen molecule alleviates TNFα-induced cell injury in osteoblast.
This animal study examined Treatment with hydrogen molecule alleviates TNFα-induced cell injury in osteoblast. The abstract describes Rat model. The abstract reports: Recently, it has been demonstrated that hydrogen gas, known as a novel antioxidant, can exert therapeutic anti-inflammatory effect in many diseases. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages.
This animal study examined Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: However, we have recently demonstrated that hydrogen inhibits type I allergy through modulating intracellular signal transduction. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress.
This animal study examined Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress. The abstract describes Mouse model. The abstract reports: Rheumatoid arthritis (RA) is a chronic inflammatory disease which results in progressive destruction of the joint. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo.
This animal study examined Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The results showed that the number of senescence-associated β-galactosidase (SA-β-Gal) positive cells was reduced in BMSCs from rats treated with HRS. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen suppresses activated Wnt/β-catenin signaling.
This animal study examined Molecular hydrogen suppresses activated Wnt/β-catenin signaling. The abstract describes Rat model; hydrogen delivered as hydrogen water. The abstract reports: We found that H2 suppresses activated Wnt/β-catenin signaling by promoting phosphorylation and degradation οf β-catenin. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?
This in vitro or cellular study examined Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?. The abstract describes Cell culture / in vitro model. The abstract reports: Recent studies in animal models of focal or global cerebral ischemia and cerebral ischemia in humans suggest that hydrogen has pleiotropic neuroprotective properties. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models.
This animal study examined Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models. The abstract describes Mouse model; reported duration 60 days. The abstract reports: These results suggest that H therapy can mitigate toxic metabolites in the astrocytic urea cycle, thereby reducing neurodegeneration and memory loss in AD. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels.
This animal study examined Hydrogen-rich saline attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP levels. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Our results suggest that HS attenuates isoflurane-induced caspase-3 activation and cognitive impairment via inhibition of isoflurane-induced oxidative stress, mitochondrial dysfunction, and reduction in ATP…. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells.
This in vitro or cellular study examined Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells. The abstract describes Cell culture / in vitro model; hydrogen delivered as hydrogen water. The abstract reports: Previous evidence suggests Aβ-induced neurotoxicity is linked to the stimulation of reactive oxygen species (ROS) production. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreThe role of hydrogen therapy in Alzheimer’s disease management: Insights into mechanisms, administration routes, and future challenges.
This narrative review examined The role of hydrogen therapy in Alzheimer’s disease management: Insights into mechanisms, administration routes, and future challenges. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreMolecular hydrogen therapy: A “democratic” emerging strategy against aging and age-related diseases.
This narrative review examined Molecular hydrogen therapy: A “democratic” emerging strategy against aging and age-related diseases. The abstract describes Published literature review. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Indirectly Suppresses Increases in Hydrogen Peroxide in Cytoplasmic Hydroxyl Radical-Induced Cells and Suppresses Cellular Senescence.
This in vitro or cellular study examined Hydrogen Indirectly Suppresses Increases in Hydrogen Peroxide in Cytoplasmic Hydroxyl Radical-Induced Cells and Suppresses Cellular Senescence. The abstract describes Cell culture / in vitro model. This is an automated editorial draft based on the abstract and requires source review before publication.
Read MoreHydrogen Treatment Protects against Cell Death and Senescence Induced by Oxidative Damage.
This animal study examined Hydrogen Treatment Protects against Cell Death and Senescence Induced by Oxidative Damage. The abstract describes Mouse model; hydrogen delivered as hydrogen water. The abstract reports: Thus, this study showed the antioxidant and anti-senescence effects of hydrogen water. This is an automated editorial draft based on the abstract and requires source review before publication.
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