[Effect of hydrogen-rich water on the CD34 expression in lesion boundary brain tissue of rats with traumatic brain injury].

This animal study examined [Effect of hydrogen-rich water on the CD34 expression in lesion boundary brain tissue of rats with traumatic brain injury]. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: NSS scores in TBI and TBI+HW groups showed a decreased tendency with time prolongation after TBI, which showed more significant in TBI+HW group, NSS…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effects of hydrogen-rich water on the expression of aquaporin 1 in the cerebral cortex of rat with traumatic brain injury].

This animal study examined [Effects of hydrogen-rich water on the expression of aquaporin 1 in the cerebral cortex of rat with traumatic brain injury]. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 5 days. The abstract reports: The up-regulation of AQP1 mRNA and protein in rats' cerebral cortex after TBI perhaps participates in edema formation which might be involved in the…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effect of hydrogen-rich water on the chondriosome damage and cytokines in brain tissue of rats with traumatic brain injury].

This animal study examined [Effect of hydrogen-rich water on the chondriosome damage and cytokines in brain tissue of rats with traumatic brain injury]. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen. The abstract reports: NSS scores in TBI and TBI+HW groups showed a decreased tendency with time prolongation after TBI. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Effects of hydrogen rich water on the expression of Nrf 2 and the oxidative stress in rats with traumatic brain injury].

This animal study examined [Effects of hydrogen rich water on the expression of Nrf 2 and the oxidative stress in rats with traumatic brain injury]. The abstract describes Rat model; hydrogen delivered as hydrogen water and injected or infused hydrogen; reported duration 5 days. The abstract reports: Compared with TBI group, the parameters in HW group were improved, and they were similar as sham operation group. (3) RT-qPCR: no significant difference…. This is an automated editorial draft based on the abstract and requires source review before publication.

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[Role of FOXO3a in process of hydrogen-rich saline attenuating global cerebral ischemia-reperfusion injury in rats].

This animal study examined [Role of FOXO3a in process of hydrogen-rich saline attenuating global cerebral ischemia-reperfusion injury in rats]. The abstract describes Rat model; sample size 12; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: Hydrogen-rich saline can attenuate global cerebral I/R injure through inhibiting JNK, reducing the expression of FOXO3a. This is an automated editorial draft based on the abstract and requires source review before publication.

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The Role of Gaseous Molecules in Traumatic Brain Injury: An Updated Review.

This narrative review examined The Role of Gaseous Molecules in Traumatic Brain Injury: An Updated Review. The abstract describes Published literature review. The abstract reports: Biological gaseous molecules including nitric oxide (NO), carbon monoxide (CO), hydrogen sulfide (HS), and molecular hydrogen (H) have been found to play critical roles…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Nuclear factor-κB/Bcl-XL pathway is involved in the protective effect of hydrogen-rich saline on the brain following experimental subarachnoid hemorrhage in rabbits.

This animal study examined Nuclear factor-κB/Bcl-XL pathway is involved in the protective effect of hydrogen-rich saline on the brain following experimental subarachnoid hemorrhage in rabbits. The abstract describes Rabbit model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Correspondingly, TUNEL staining demonstrated obvious neuronal apoptosis following SAH. This is an automated editorial draft based on the abstract and requires source review before publication.

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Protective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines.

This animal study examined Protective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: Here, we found that HS treatment significantly reduced infarct volume and improved neurobehavioral outcomes at 24h, 48h and 72h after pMCAO operation in a…. This is an automated editorial draft based on the abstract and requires source review before publication.

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Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression.

This animal study examined Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression. The abstract describes Rat model. The abstract reports: Behaviorally, rats in the lactulose administration group won higher neurological scores and showed shorter escape latency time in the Morris test. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice.

This animal study examined Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice. The abstract describes Mouse model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results showed that HS treatment significantly improved brain edema and decreased infarct volume. This is an automated editorial draft based on the abstract and requires source review before publication.

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Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats.

This animal study examined Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β Signaling Pathway in Rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline and injected or infused hydrogen. The abstract reports: The PI3K/Akt/GSK3β signaling pathway plays an important role in the mechanism of CPB-induced brain injury. HRS can reduce CPB-induced brain injury and inhibit CMEC…. This is an automated editorial draft based on the abstract and requires source review before publication.

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The protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats.

This animal study examined The protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats. The abstract describes Rat model; hydrogen delivered as hydrogen-rich saline. The abstract reports: The results suggest that the neuroprotective effects of hydrogen may be mediated by promoting HO-1 expression and attenuated the oxidative injury. This is an automated editorial draft based on the abstract and requires source review before publication.

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Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition.

This animal study examined Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition. The abstract describes Mouse model. The abstract reports: 2% H can protect against TBI-induced lung injury by inhibiting NLRP3 inflammasome activation, thereby alleviating inflammation and inhibiting apoptosis. This is an automated editorial draft based on the abstract and requires source review before publication.

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Magnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage.

This animal study examined Magnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage. The abstract describes Mouse model; hydrogen delivered as hydrogen inhalation. The abstract reports: RESULTS: MGNs exhibited a two-dimensional structure and enabled sustained hydrogen release, particularly under acidic conditions. This is an automated editorial draft based on the abstract and requires source review before publication.

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Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats – A possible new hydrogen resource for clinical use.

This animal study examined Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats – A possible new hydrogen resource for clinical use. The abstract describes Rat model; hydrogen delivered as hydrogen inhalation. The abstract reports: Pathologically, tissues from rats in hydrogen inhalation group showed no significant difference compared with the control group in HE staining pictures. This is an automated editorial draft based on the abstract and requires source review before publication.

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