Hydrogen Research Study
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Human clinical evidenceHuman Clinical Studyhydrogen-rich water

Acute effect of hydrogen-rich water on physical, perceptual and cardiac responses during aerobic and anaerobic exercises: a randomized, placebo-controlled, double-blinded cross-over trial.

Nidhal Jebabli, Nejmeddine Ouerghi, Wissal Abassi, Fatma Hilal Yagin, Mariem Khlifi, Manar Boujabli, Anissa Bouassida, Abderraouf Ben Abderrahman, Luca Paolo Ardigò · Frontiers in physiology · 2023

Research-use notice

Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image
Primary topic Cardiovascular Health
Evidence type Human clinical evidence
Publication type Human Clinical Study
Hydrogen method hydrogen-rich water

H2HUBB TAKEAWAY

In In a randomized, double-blind study design, all players ingested 500 mL of HRW or placebo (PLA) supplement 30 min before the start of the tests, 500 mL of HRW can significantly improve HRpeak, time to exhaustion, RPE, with no significant effect on MAS, jumping performance in amateur endurance athletes. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.

What the Findings Mean

H2HUBB reviewed how hydrogen-rich water affected the outcomes measured in In a randomized, double-blind study design, all players ingested 500 mL of HRW or placebo (PLA) supplement 30 min before the start of the tests. 500 mL of HRW can significantly improve HRpeak, time to exhaustion, RPE, with no significant effect on MAS, jumping performance in amateur endurance athletes.

What the Researchers Studied

The researchers studied In a randomized, double-blind study design, all players ingested 500 mL of HRW or placebo (PLA) supplement 30 min before the start of the tests. The study used a randomized, double-blind, placebo-controlled human clinical trial. The comparison condition was placebo.

What Effects Did Molecular Hydrogen Have?

500 mL hydrogen-rich water per reported dose; dissolved H₂ concentration was not reported in the available source text, so H2HUBB did not estimate milligrams of H₂. 500 mL of HRW can significantly improve HRpeak, time to exhaustion, RPE, with no significant effect on MAS, jumping performance in amateur endurance athletes.

Why These Findings Matter

These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study and contribute to the growing body of molecular-hydrogen research.

How Strong Is This Evidence?

This is human clinical evidence from a randomized, double-blind, placebo-controlled human clinical trial. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.

Technical Study Details

H2HUBB classifies this publication as human clinical study with human clinical evidence. The research population or model was In a randomized, double-blind study design, all players ingested 500 mL of HRW or placebo (PLA) supplement 30 min before the start of the tests. The reported sample size was 2. The study used a randomized, double-blind, placebo-controlled human clinical trial. The hydrogen delivery method was hydrogen-rich water. H2HUBB translates the reported hydrogen dose as 500 mL hydrogen-rich water per reported dose; dissolved H₂ concentration was not reported in the available source text, so H2HUBB did not estimate milligrams of H₂.

Limitations and Safety

No separate limitations or safety findings were identified in the source text available to H2HUBB.

Original Study and H2HUBB Research Context

H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.