Acute Supplementation with Molecular Hydrogen Benefits Submaximal Exercise Indices. Randomized, Double-Blinded, Placebo-Controlled Crossover Pilot Study.
Tyler W LeBaron, Abigail J Larson, Shigeo Ohta, Toshio Mikami, Jordon Barlow, Josh Bulloch, Mark DeBeliso · Journal of lifestyle medicine · 2019
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In 8 healthy participants, HRW decreased exercising HR during minutes 1-9 of the graded exercise test (121 ± 26 bpm) compared to placebo (126 ± 26 bpm) and baseline (124 ± 27 bpm) (p < 0.001) without substantially influencing VO2. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence exercise performance and recovery in healthy adults.
What the Findings Mean
H2HUBB reviewed how hydrogen-rich water affected the outcomes measured in 8 healthy participants. HRW decreased exercising HR during minutes 1-9 of the graded exercise test (121 ± 26 bpm) compared to placebo (126 ± 26 bpm) and baseline (124 ± 27 bpm) (p < 0.001) without substantially influencing VO2.
What the Researchers Studied
The researchers studied 8 healthy participants. The study used a randomized, double-blind, placebo-controlled, crossover human clinical trial. The comparison condition was placebo.
What Effects Did Molecular Hydrogen Have?
HRW was delivered using the hydrogen-producing tablets, DrinkHRW (5 mg of H₂). HRW decreased exercising HR during minutes 1-9 of the graded exercise test (121 ± 26 bpm) compared to placebo (126 ± 26 bpm) and baseline (124 ± 27 bpm) (p < 0.001) without substantially influencing VO2. The authors concluded that acute supplementation of DrinkHRW tablets may benefit submaximal aerobic exercise performance by lowering exercising HR.
Why These Findings Matter
These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence exercise performance and recovery in healthy adults and contribute to the growing body of molecular-hydrogen research.
How Strong Is This Evidence?
This is human clinical evidence from a randomized, double-blind, placebo-controlled, crossover human clinical trial. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.
Technical Study Details
H2HUBB classifies this publication as human clinical study with human clinical evidence. The research population or model was 8 healthy participants. The reported sample size was 4. The study used a randomized, double-blind, placebo-controlled, crossover human clinical trial. The hydrogen delivery method was hydrogen-rich water.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.