Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function.
Takaaki Sakai, Bunpei Sato, Koji Hara, Yuichi Hara, Yuji Naritomi, Samon Koyanagi, Hiroshi Hara, Tetsuhiko Nagao, Toru Ishibashi · Vascular health and risk management · 2014
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H2HUBB TAKEAWAY
In 8 participants, fMD increased in the high-H₂ group (eight males; eight females) from 6.80%±1.96% to 7.64%±1.68% (mean ± standard deviation) and decreased from 8.07%±2.41% to 6.87%±2.94% in the placebo group (ten males; eight females).
What the Researchers Studied
Molecular hydrogen (H₂) neutralizes detrimental ROS, especially the hydroxyl radical.
How the Study Was Conducted
Randomized, placebo-controlled human clinical trial.
How Molecular Hydrogen Was Used
The subjects were randomly divided into two groups: the high-H₂ group, who drank high-H₂ water containing 7 ppm H₂ (3.5 mg H₂ in 500 mL water); and the placebo group. After measurement of diameter of the BA and FMD at baseline, volunteers drank the high-H₂ water or placebo water immediately and with a 30-minute interval; FMD was compared to baseline.
What the Researchers Found
FMD increased in the high-H₂ group (eight males; eight females) from 6.80%±1.96% to 7.64%±1.68% (mean ± standard deviation) and decreased from 8.07%±2.41% to 6.87%±2.94% in the placebo group (ten males; eight females).