Effect of eradicating hydrogen-forming small intestinal bacterial overgrowth with rifaximin on body weight change.
Seok-Hoon Lee, Doo-Yeoun Cho, Nam-Seok Joo, Kyu-Nam Kim · Medicine · 2019
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
This narrative review examined the available molecular-hydrogen literature. A total of 153 patients were enrolled in the study and divided into quartiles according to body mass index (BMI) and body weight.In the lowest body weight quartile, the BMI and body weight were significantly increased (0.4 kg/m, P =.038; 0.6 kg, P =.010, respectively) in patients with negative lactulose hydrogen breath tests after rifaximin treatment. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
What the Findings Mean
H2HUBB reviewed this publication as a synthesis of molecular-hydrogen research and summarizes the outcomes emphasized by the authors. 4 the researchers found that eradicating hydrogen-forming SIBO by rifaximin treatment increased BMI and body weight in the lowest body weight group.
What the Researchers Studied
The authors reviewed effect of eradicating hydrogen-forming small intestinal bacterial overgrowth with rifaximin on body weight change.
What Effects Did Molecular Hydrogen Have?
Reported treatment duration: 12 weeks. 4 the researchers found that eradicating hydrogen-forming SIBO by rifaximin treatment increased BMI and body weight in the lowest body weight group.
Why These Findings Matter
The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
How Strong Is This Evidence?
This is review or synthesis evidence (narrative review).
Technical Study Details
H2HUBB classifies this publication as narrative review with review or synthesis evidence. The reported sample size was 153. The study used a narrative review. The reported treatment duration was 12 weeks.
Limitations and Safety
No separate limitations or safety findings were identified in the current-study source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.