Effect of hydrogen intervention on refractory wounds after radiotherapy: A case report.
Peng-Xiang Zhao, Rui-Liu Luo, Zheng Dang, You-Bin Wang, Xu-Juan Zhang, Zi-Yi Liu, Xiao-Hu Wen, Meng-Yu Liu, Ming-Zi Zhang, Yao Mawulikplimi Adzavon, Xue-Mei Ma · World journal of clinical cases · 2022
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In participants with keloids who receive radiotherapy (RT) after surgery can develop refractory wounds that cannot be healed by the patient's, after HI therapy, the patient showed superior progress in reepithelialization and wound repair, with eventual wound closure in 6 mo, in comparison with the previous failures of hyperbaric oxygen and recombinant bovine basic fibroblast growth factor therapies. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
What the Findings Mean
H2HUBB reviewed how molecular hydrogen affected the outcomes measured in participants with keloids who receive radiotherapy (RT) after surgery can develop refractory wounds that cannot be healed by the patient's. After HI therapy, the patient showed superior progress in reepithelialization and wound repair, with eventual wound closure in 6 mo, in comparison with the previous failures of hyperbaric oxygen and recombinant bovine basic fibroblast growth factor therapies.
What the Researchers Studied
The researchers studied participants with keloids who receive radiotherapy (RT) after surgery can develop refractory wounds that cannot be healed by the patient's.
What Effects Did Molecular Hydrogen Have?
After HI therapy, the patient showed superior progress in reepithelialization and wound repair, with eventual wound closure in 6 mo, in comparison with the previous failures of hyperbaric oxygen and recombinant bovine basic fibroblast growth factor therapies.
Why These Findings Matter
These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study and contribute to the growing body of molecular-hydrogen research.
How Strong Is This Evidence?
This is human clinical evidence from a case report. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.
Technical Study Details
H2HUBB classifies this publication as case report with human clinical evidence. The research population or model was participants with keloids who receive radiotherapy (RT) after surgery can develop refractory wounds that cannot be healed by the patient's.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.