Effects of endurance exercise on physiologic complexity of the hemodynamics in prefrontal cortex.
Yinglu Hong, Dapeng Bao, Brad Manor, Yuncong Zhou, Junhong Zhou · Neurophotonics · 2024
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In participants, the fNIRS complexity was significantly greater in the conditions from 25% to 100% of the physical load (p<0.0005) compared with the baseline and after intaking H₂ before exercise; this increase of fNIRS complexity was significantly greater compared with the control (p=0.001∼0.01). These findings add human evidence that helps define the outcomes that did and did not change with molecular hydrogen in this study.
What the Findings Mean
H2HUBB reviewed how inhaled hydrogen gas was evaluated in this publication and summarizes the source-grounded findings below. The fNIRS complexity was significantly greater in the conditions from 25% to 100% of the physical load (p<0.0005) compared with the baseline and after intaking H₂ before exercise; this increase of fNIRS complexity was significantly greater compared with the control (p=0.001∼0.01).
What the Researchers Studied
The comparison condition was placebo.
What Effects Did Molecular Hydrogen Have?
Reported treatment duration: 20 min. The fNIRS complexity was significantly greater in the conditions from 25% to 100% of the physical load (p<0.0005) compared with the baseline and after intaking H₂ before exercise; this increase of fNIRS complexity was significantly greater compared with the control (p=0.001∼0.01). The authors concluded that these observations suggest that fNIRS complexity would be a marker that captures the adaptive capacity of PFC to endurance exercise and to the effects of interventions on PFC hemodynamics.
Why These Findings Matter
This publication adds useful evidence about where molecular hydrogen did and did not change the measured outcomes, helping define the larger therapeutic evidence base.
How Strong Is This Evidence?
This is human clinical evidence from a human clinical study. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.
Technical Study Details
H2HUBB classifies this publication as human clinical study with human clinical evidence. The reported sample size was 17. The hydrogen delivery method was inhaled hydrogen gas. The reported treatment duration was 20 min.
Limitations and Safety
Reported limitations: Some limitations should be noted in this pilot study.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.