Shop Hydrogen Products
Hydrogen Research Study
← Back to Research Library
Preclinical animal evidenceAnimal studyOther or not reported

Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice.

Yasuki Higashimura, Yasunori Baba, Ryo Inoue, Tomohisa Takagi, Kazuhiko Uchiyama, Katsura Mizushima, Yasuko Hirai, Chihiro Ushiroda, Yoshinori Tanaka, Yuji Naito · Medical gas research · 2018

View Original Study View Full Text

Research-use notice

Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image
Primary topic Molecular Hydrogen Overview
Evidence type Preclinical animal evidence
Publication type Animal study
Hydrogen method Other or not reported

H2HUBB TAKEAWAY

These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.

What the Researchers Studied

Mice

Biological or Mechanistic Findings

Increasing evidence indicates that molecular hydrogen-dissolved alkaline electrolyzed water (AEW) has various physiological activities such as antioxidative activity.

Authors’ Conclusion

These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.

CONTINUE EXPLORING

Related Molecular Hydrogen Studies

Preclinical animal evidenceAnimal studyOther or not reported

Hydrogen gas inhalation alleviated cerebral ischemia/reperfusion injury by regulating mitophagy in SH-SY5Y cells and mice via PTEN-induced kinase 1/Parkin pathway.

Zhenkui Wang, Wei Feng, Jie Zhou, Lei Huang, Chuanfeng Fang, Jiarong Yuan, Hongsheng Chen, Li Xue · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2026

In SH-SY5Y cells, H₂ treatment significantly improved cell viability, attenuated oxidative stress and mitochondrial dysfunction, and enhanced mitophagy via activation of the PINK1/Parkin pathway. These results are preclinical and suggest molecular hydrogen's therapeutic potential…

Primary topic
Molecular Hydrogen Overview
Delivery method
Other or not reported
Study ID
DOI: 10.1016/j.jstrokecerebrovasdis.2026.108645
View Study View Source
Preclinical animal evidenceAnimal studyOther or not reported

[Role of Nrf2 in the protective effects of hydrogen against cerebral dysfunction in septic mice].

Lingling Liu, Keliang Xie, Hongguang Chen, Xiaoqing Dong, Guolin Wang, Yonghao Yu · Zhonghua wei zhong bing ji jiu yi xue · 2014

In mice, compared with the sham operation and hydrogen control groups, in the sepsis group, the number of normal pyramidal neurons in the hippocampal CA1 region was markedly reduced, the apoptotic index was marked…

Primary topic
Molecular Hydrogen Overview
Delivery method
Other or not reported
Main limitation
Preclinical animal findings may not translate directly to human outcomes. The intervention or follow-up…
Study ID
DOI: 10.3760/cma.j.issn.2095-4352.2014.09.005
View Study View Source
Preclinical animal evidenceAnimal studyhydrogen-rich water

[Alleviating effects of hydrogen on hyperhomocysteinemia and fatty liver induced by high-methionine diet].

Wen-Bin Chu, Tian-Qi Ding, Bo Wen, Jun-Yu Lu, Rong Fan, Xue-Wei Chen · Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology · 2022

Compared with the HMD group rats, the HMD+HRW group rats showed a significant decrease in Hcy in the blood, reduced liver damage, and increased Hcy metabolism key enzyme activity and mRNA expression in the…

Primary topic
Molecular Hydrogen Overview
Delivery method
hydrogen-rich water
Main limitation
Preclinical animal findings may not translate directly to human outcomes.
Study ID
DOI: 10.12047/j.cjap.6382.2022.143
View Study View Source