Effects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder.
Yong Wang, Mengmeng Wang, Bing Xie, Di Wen, Wenbo Li, Meiqi Zhou, Xintao Wang, Yun Lu, Bin Cong, Zhiyu Ni, Chunling Ma · Brain research bulletin · 2023
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
Hydrogen intervention, including drinking and inhaling, significantly alleviated mental disorders induced by METH abuse, and the inhalation of hydrogen also altered gut microbiota profiles in the METH abusers. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
What the Findings Mean
H2HUBB reviewed how inhaled hydrogen gas was evaluated in this publication and summarizes the source-grounded findings below. Hydrogen intervention, including drinking and inhaling, significantly alleviated mental disorders induced by METH abuse, and the inhalation of hydrogen also altered gut microbiota profiles in the METH abusers.
What the Researchers Studied
The comparison condition was control condition or baseline measurements.
What Effects Did Molecular Hydrogen Have?
Hydrogen intervention, including drinking and inhaling, significantly alleviated mental disorders induced by METH abuse, and the inhalation of hydrogen also altered gut microbiota profiles in the METH abusers. The authors concluded that these results suggest that hydrogen intervention has potential therapeutic applicability in the treatment of mental disorders in METH abusers. Molecular hydrogen (H₂) is spontaneously produced by intestinal bacteria in the process of anaerobic metabolism, which is the main pathway for H₂ production in vivo.
Why These Findings Matter
These findings add evidence supporting molecular hydrogen's therapeutic potential within the biological process and outcomes directly measured in this publication and contribute to the growing body of molecular-hydrogen research.
How Strong Is This Evidence?
H2HUBB classifies this publication as other research and interprets only the outcomes directly supported by the source record.
Technical Study Details
H2HUBB classifies this publication as other research with other supported evidence. The hydrogen delivery method was inhaled hydrogen gas.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.