Electrolyzed Hydrogen Water Alleviates Abdominal Pain through Suppression of Colonic Tissue Inflammation in a Rat Model of Inflammatory Bowel Disease.
Di Hu, Tianliang Huang, Mika Shigeta, Yuta Ochi, Shigeru Kabayama, Yasuyoshi Watanabe, Yilong Cui · Nutrients · 2022
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
Electrolyzed hydrogen water (EHW) has been shown to alleviate inflammation in several diseases, such as renal disease and polymyositis/dermatomyositis. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
What the Researchers Studied
The study examined rats.
How Molecular Hydrogen Was Used
Molecular hydrogen was administered as electrolyzed hydrogen water (ehw) has been shown to alleviate inflammation in several diseases, such as renal disease and polymyositis/dermatomyositis.
What the Researchers Found
The production of proinflammatory cytokines in inflamed colon tissue was also decreased significantly.
H₂ Mechanisms / Biological Findings
The source material reviewed did not establish a specific molecular hydrogen mechanism for the reported findings.
Authors’ Conclusion
The authors concluded that these results suggest that the EHW prevented the overproduction of ROS due to its powerful free-radical scavenging ability and blocked the crosstalk between oxidative stress and inflammation, thereby suppressing colonic inflammation and alleviating abdominal pain.