H2 metabolism is widespread and diverse among human colonic microbes.
Patricia G Wolf, Ambarish Biswas, Sergio E Morales, Chris Greening, H Rex Gaskins · Gut microbes · 2016
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
The study reports that In this work, we surveyed the genomic and metagenomic distribution of hydrogenase-encoding genes in the human colon to infer dominant mechanisms of H2 cycling.
What the Researchers Studied
Source-reported study description: Microbial molecular hydrogen (H2) cycling is central to metabolic homeostasis and microbial composition in the human gastrointestinal tract.
Source-reported study description: Molecular H2 is produced as an endproduct of carbohydrate fermentation and is reoxidised primarily by sulfate-reduction, acetogenesis, and methanogenesis.
What the Study Found
The authors reported: the enzymatic basis for these processes is incompletely understood and the hydrogenases responsible have not been investigated.
What the Findings Mean
The authors concluded/reported: In this work, we surveyed the genomic and metagenomic distribution of hydrogenase-encoding genes in the human colon to infer dominant mechanisms of H2 cycling.
Study Details
Publication type: other_research
Evidence source level: B_ABSTRACT
Original scholarly source: https://pubmed.ncbi.nlm.nih.gov/27123663/