Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model.
Keliang Xie, Yonghao Yu, Zishen Zhang, Wenbo Liu, Yuping Pei, Lize Xiong, Lichao Hou, Guolin Wang · Shock (Augusta, Ga.) · 2010
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Independent study record
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H2HUBB TAKEAWAY
The researchers found that the beneficial effects of H₂ treatment on ZY-induced organ damage were associated with the decreased levels of oxidative product, increased activities of antioxidant enzyme, and reduced levels of early and late proinflammatory cytokines in serum and tissues. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
What the Researchers Found
The researchers found that the beneficial effects of H₂ treatment on ZY-induced organ damage were associated with the decreased levels of oxidative product, increased activities of antioxidant enzyme, and reduced levels of early and late proinflammatory cytokines in serum and tissues.
Authors’ Conclusion
The authors concluded that in conclusion, this study provides evidence that H₂ treatment protects against multiple organ damages in ZY-induced generalized inflammation model, suggesting the potential use of H₂ as a therapeutic agent in the therapy of conditions associated with inflammation-related multiple organ dysfunction syndrome. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.