Hydrogen Gas Treatment Improves Postoperative Delirium and Cognitive Dysfunction in Elderly Noncardiac Patients.
Hua Lin, Jian Du, Zhigang Tian, Yonghao Yu, Yan Cui, Keliang Xie · Journal of personalized medicine · 2022
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In 184 patients, the numerical rating scale (NRS) pain scores were higher in the hydrogen group (4.08 ± 1.77) than the control group (3.54 ± 1.77) on day 1 (p < 0.05); however, the mean difference between the two groups was small (1 to 1.6).
What the Researchers Studied
The researchers used prophylactic inhalation of hydrogen gas in elderly patients undergoing elective surgery to compare their occurrence of postoperative delirium with that of controls.
How the Study Was Conducted
Randomized human clinical trial.
How Molecular Hydrogen Was Used
A total of 184 patients aged ≥ 65 years were enrolled and randomized into either a control group or a hydrogen inhalation group.
What the Researchers Found
The numerical rating scale (NRS) pain scores were higher in the hydrogen group (4.08 ± 1.77) than the control group (3.54 ± 1.77) on day 1 (p < 0.05); however, the mean difference between the two groups was small (1 to 1.6).