Hydrogen-rich saline may be an effective and specific novel treatment for osteoradionecrosis of the jaw.
Yuanli Chen, Chunlin Zong, Yuxuan Guo, Lei Tian · Therapeutics and clinical risk management · 2015
Research-use notice
Independent study record
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H2HUBB TAKEAWAY
In Reducing the hydroxyl radical can distinctly improve the protection of cells from radiation damage, hydrogen-rich saline is an alternative form of molecular hydrogen that has been widely used in many studies, including metabolic syndrome, cerebral, hepatic, myocardial ischemia/reperfusion, and liver injuries with obstructive jaundice, with beneficial results. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.
What the Researchers Tested
In vitro cell-culture laboratory experiment.
Laboratory Model
Reducing the hydroxyl radical can distinctly improve the protection of cells from radiation damage.
How Molecular Hydrogen Was Used
Hydrogen, a therapeutic medical gas, can exert antioxidant activity via selectively reducing cytotoxic reactive oxygen species such as hydroxyl radicals. Hydrogen-rich saline is an alternative form of molecular hydrogen that has been widely used in many studies, including metabolic syndrome, cerebral, hepatic, myocardial ischemia/reperfusion, and liver injuries with obstructive jaundice, with beneficial results. The researchers hypothesized that hydrogen-rich saline might be an effective and specific method of managing and preventing osteoradionecrosis of the jaw.
What Molecular Hydrogen Changed
Hydrogen-rich saline is an alternative form of molecular hydrogen that has been widely used in many studies, including metabolic syndrome, cerebral, hepatic, myocardial ischemia/reperfusion, and liver injuries with obstructive jaundice, with beneficial results.
Authors’ Conclusion
These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.