Hydrogen Therapy and Its Future Prospects for Ameliorating COVID-19: Clinical Applications, Efficacy, and Modality.
Ishrat Perveen, Bakhtawar Bukhari, Mahwish Najeeb, Sumbal Nazir, Tallat Anwar Faridi, Muhammad Farooq, Qurat-Ul-Ain Ahmad, Manal Abdel Haleem A Abusalah, Thana' Y ALjaraedah, Wesal Yousef Alraei, Ali A Rabaan, Kirnpal Kaur Banga Singh, Mai Abdel Haleem A Abusalah · Biomedicines · 2023
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
This narrative review examined the available molecular-hydrogen literature. The recommendations developed by China suggest that the inhalation of hydrogen molecules is currently advised in COVID-19 pneumonia treatment. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
What the Findings Mean
H2HUBB reviewed this publication as a synthesis of molecular-hydrogen research and summarizes the outcomes emphasized by the authors. The recommendations developed by China suggest that the inhalation of hydrogen molecules is currently advised in COVID-19 pneumonia treatment.
What the Researchers Studied
The authors reviewed hydrogen Therapy and Its Future Prospects for Ameliorating COVID-19: Clinical Applications, Efficacy, and Modality.
What Effects Did Molecular Hydrogen Have?
It has been concluded that H₂ intervention can control the production of inflammatory cytokines, reduce or prevent both in vitro and in vivo cellular apoptotic damages, and scavenge free radicals, demonstrating the therapeutic benefit of H₂. In patients with mild-to-moderate disease symptoms, H₂ administration has been reported to improve recovery through the abatement of the hyperinflammatory cytokine cascade and a reduction in inhalation resistance, as it functions as an effective anti-inflammatory and antioxidative agent. The recommendations developed by China suggest that the inhalation of hydrogen molecules is currently advised in COVID-19 pneumonia treatment. This review has also found that molecular hydrogen therapies effectively remediated the life-threatening consequences of SARS-CoV-2 infection.
Why These Findings Matter
The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
How Strong Is This Evidence?
This is review or synthesis evidence (narrative review).
Technical Study Details
H2HUBB classifies this publication as narrative review with review or synthesis evidence. The study used a narrative review. The hydrogen delivery method was inhaled hydrogen gas.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.