Hydrogen therapy: from mechanism to cerebral diseases.
Cheng-Lin Liu, Kai Zhang, Gang Chen · Medical gas research · 2016
Research-use notice
Independent study record
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H2HUBB TAKEAWAY
This narrative review examined the available evidence on molecular hydrogen. The medicinal value of hydrogen (H₂) was ignored prior to research illustrating that inhalation of 2% H₂ can significantly decrease the damage of cerebral ischemia/reperfusion caused by oxidative stress via selective elimination of hydroxyl freebase (OH) and peroxynitrite anion (ONOO-). The reviewed evidence supports molecular hydrogen's therapeutic potential. Additional well-designed studies are needed to clarify clinical safety and effectiveness.
What the Review Examined
The review examined hydrogen therapy: from mechanism to cerebral diseases.
Main Findings Across the Literature
The medicinal value of hydrogen (H₂) was ignored prior to research illustrating that inhalation of 2% H₂ can significantly decrease the damage of cerebral ischemia/reperfusion caused by oxidative stress via selective elimination of hydroxyl freebase (OH) and peroxynitrite anion (ONOO-).
H₂ Mechanisms / Biological Findings
The medicinal value of hydrogen (H₂) was ignored prior to research illustrating that inhalation of 2% H₂ can significantly decrease the damage of cerebral ischemia/reperfusion caused by oxidative stress via selective elimination of hydroxyl freebase (OH) and peroxynitrite anion (ONOO-).
Authors’ Conclusion
A distinct authors’ conclusion was not available in the source material reviewed by H2HUBB.