Hydrogen Treatment Protects Mice Against Chronic Pancreatitis by Restoring Regulatory T Cells Loss.
Luguang Chen, Chao Ma, Yun Bian, Jing Li, Tiegong Wang, Li Su, Jianping Lu · Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2017
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Independent study record
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H2HUBB TAKEAWAY
The researchers found that hydrogen treatment significantly improved multiple symptoms of chronic pancreatitis. These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.
What the Researchers Tested
In vitro cell-culture laboratory experiment.
Laboratory Model
Tissue inflammation, damage and fibrosis were analyzed on HE, TUNEL, MPO, and sirius staining.
How Molecular Hydrogen Was Used
By using an L-arginine induced chronic pancreatitis mouse model, the researchers tested the therapeutic potential of hydrogen, a strong hydroxyl radicals scavenger, in the chronic pancreatitis model.
What Molecular Hydrogen Changed
The researchers found that hydrogen treatment significantly improved multiple symptoms of chronic pancreatitis.
Authors’ Conclusion
These findings come from a laboratory model and suggest molecular hydrogen's biological potential. Further research is needed to determine clinical relevance.