Impact of hydrogen-rich gas mixture inhalation through nasal cannula during post-exercise recovery period on subsequent oxidative stress, muscle damage, and exercise performances in men.
Yudai Shibayama, Shohei Dobashi, Takaaki Arisawa, Tamotsu Fukuoka, Katsuhiro Koyama · Medical gas research · 2020
Research-use notice
Independent study record
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H2HUBB TAKEAWAY
In 8 physically active participants, after exercise HG inhalation attenuated the increase in urinary 8-hydroxydeoxyguanosine excretion rate (P < 0.05), a DNA oxidation marker, and the reduction in the countermovement jump height (P < 0.05), compared with Placebo inhalation.
What the Researchers Studied
8 physically active participants.
How the Study Was Conducted
Double-blind, placebo-controlled human clinical trial.
How Molecular Hydrogen Was Used
Eight physically active male volunteers inhaled HG (estimated fraction of inspired oxygen and hydrogen were 21.57 and 4.08% at most, respectively) or normal gas (placebo, ambient air 400 m above sea level) during a 60-minute recovery phase after oxidative stress-inducing exercise) completion comprising 30-minute treadmill running at an intensity corresponding to 75% of maximal oxygen uptake and squat jumps (5 sets × 10 repetitions).
What the Researchers Found
After exercise HG inhalation attenuated the increase in urinary 8-hydroxydeoxyguanosine excretion rate (P < 0.05), a DNA oxidation marker, and the reduction in the countermovement jump height (P < 0.05), compared with Placebo inhalation.
Authors’ Conclusion
The authors concluded that these findings suggested that HG inhalation during post-exercise recovery period might improve exercise performance via reducing systemic oxidative damage.