Molecular Hydrogen: an Emerging Therapeutic Medical Gas for Brain Disorders.
Chongyun Wu, Peibin Zou, Shu Feng, Ling Zhu, Fanghui Li, Timon Cheng-Yi Liu, Rui Duan, Luodan Yang · Molecular neurobiology · 2023
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H2HUBB TAKEAWAY
This narrative review examined the available molecular-hydrogen literature. Since the landmark finding reported in 2007 found that hydrogen reduced the levels of peroxynitrite anions and hydroxyl free radicals in ischemic stroke, molecular hydrogen's antioxidative and anti-inflammatory effects have aroused widespread interest. The reviewed evidence supports molecular hydrogen's therapeutic potential. Additional well-designed studies are needed to clarify clinical safety and effectiveness.
Main Findings Across the Literature
Since the landmark finding reported in 2007 found that hydrogen reduced the levels of peroxynitrite anions and hydroxyl free radicals in ischemic stroke, molecular hydrogen's antioxidative and anti-inflammatory effects have aroused widespread interest.