Hydrogen Research Study
← Back to Research Library
Human clinical evidenceUncontrolled human studyOther or not reported

Hydrogen-Rich Medium Ameliorates Lipopolysaccharides-Induced Mitochondrial Fission and Dysfunction in Human Umbilical Vein Endothelial Cells (Huvecs) via Up-Regulating HO-1 Expression

Xie Keliang, Mao Xing, Lian Naqi, Wang Yanyan, Wang Yuzun, Chen Hongguang, Zhu Ruqing, Yu Yonghao, Wang Guolin · 2021

Research-use notice

Independent study record

Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB Research Library branded molecular hydrogen research image
Primary topic Blood Pressure and Vascular Function
Evidence type Human clinical evidence
Publication type Uncontrolled human study
Hydrogen method Other or not reported
molecular hydrogen blood pressure study 2021 research summary

The publication “Hydrogen-Rich Medium Ameliorates Lipopolysaccharides-Induced Mitochondrial Fission and Dysfunction in Human Umbilical Vein Endothelial Cells (Huvecs) via Up-Regulating HO-1 Expression” is organized in H2HUBB under the research focus molecular hydrogen blood pressure study 2021. The publication is cited as Xie Keliang, Mao Xing, Lian Naqi, Wang Yanyan, Wang Yuzun, Chen Hongguang, Zhu Ruqing, Yu Yonghao, Wang Guolin, 2021. This uncontrolled human study examined Hydrogen-Rich Medium Ameliorates Lipopolysaccharides-Induced Mitochondrial Fission and Dysfunction in Human Umbilical Vein Endothelial Cells (Huvecs) via Up-Regulating HO-1 Expression. The abstract describes Human participants. The abstract reports: It has been showed that the change of mitochondrial dynamics has been proved to be one of the main causes of death in patients…. This is an automated editorial draft based on the abstract and requires source review before publication.

Molecular hydrogen blood pressure study 2021 overview

Cell death and apoptosis were assessed using FITC annexin V and PI. Because this is human clinical evidence, relevance depends on participant selection, controls, sample size, treatment duration, adherence, outcome measures, and replication.

Study design and hydrogen intervention

Publication type: Uncontrolled human study. Evidence type: Human clinical evidence. Research model or population: Human participants. Blinding: Unknown. Control status: Unknown.

Delivery method: Other or not reported.

Reported findings and scientific interpretation

For this molecular hydrogen blood pressure study 2021, the study record reports the following: The abstract reports: It has been showed that the change of mitochondrial dynamics has been proved to be one of the main causes of death in patients…

These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.

How this research record was prepared

H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.

Limitations, safety, and original source

Limitations: The abstract alone may not report all methodological limitations; full-text review is required.

Safety: The abstract did not provide detailed safety or adverse-event information.

This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.