Molecular hydrogen exposure improves functional state of red blood cells in the early postoperative period: a randomized clinical study.
Anna Vaycheslavovna Deryugina, Darya Andreevna Danilova, Yurii Dmitrievich Brichkin, Evgenii Vladimirovich Taranov, Evgenii Ivanovich Nazarov, Vladimir Viktorovich Pichugin, Aleksandr Pavlovich Medvedev, Michail Valerevich Riazanov, Sergey Andreevich Fedorov, Yurevich Smorkalov Andrej, Evgenii Vladimirovich Makarov · Medical gas research · 2023
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In 20 patients with 20 patients referring to the Specialized Cardiosurgical Clinical Hospital, H₂ inhalation leads to improvement of functional state of red blood cells, which is accompanied by a more favorable course of the early postoperative period. These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study.
What the Findings Mean
H2HUBB reviewed how molecular hydrogen affected the outcomes measured in 20 patients with 20 patients referring to the Specialized Cardiosurgical Clinical Hospital. H₂ inhalation leads to improvement of functional state of red blood cells, which is accompanied by a more favorable course of the early postoperative period.
What the Researchers Studied
The researchers studied 20 patients with 20 patients referring to the Specialized Cardiosurgical Clinical Hospital. The study used a randomized human clinical trial. The comparison condition was control condition or baseline measurements.
What Effects Did Molecular Hydrogen Have?
First group included 12 patients (research group) who received H₂ at a concentration of 1.5-2.0% through a facemask using a breathing circuit of the ventilator together with anesthesia immediately after tracheal intubation and throughout the operation. H₂ inhalation leads to improvement of functional state of red blood cells, which is accompanied by a more favorable course of the early postoperative period.
Why These Findings Matter
These findings add human evidence supporting molecular hydrogen's therapeutic potential across the specific human outcomes evaluated in this study and contribute to the growing body of molecular-hydrogen research.
How Strong Is This Evidence?
This is human clinical evidence from a randomized human clinical trial. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.
Technical Study Details
H2HUBB classifies this publication as human clinical study with human clinical evidence. The research population or model was 20 patients with 20 patients referring to the Specialized Cardiosurgical Clinical Hospital. The reported sample size was 20. The study used a randomized human clinical trial.
Limitations and Safety
No separate limitations or safety findings were identified in the source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.