Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation
Nakayama Masaaki, Itami Noritomo, Suzuki Hodaka, Hamada Hiromi, Osaka Naoyuki, Yamamoto Ryo, Tsunoda Kazumasa, Nakano Hirofumi, Watanabe Kimio, Zhu Wan-Jun, Maruyama Yukio, Terawaki Hiroyuki, Kabayama Shigeru, Nakazawa Ryoichi, Miyazaki Mariko, Ito Sadayoshi · PLOS ONE · 2017
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
The publication “Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation” is organized in H2HUBB under the research focus molecular hydrogen kidney health study 2017 masaaki. The publication is cited as Nakayama Masaaki, Itami Noritomo, Suzuki Hodaka, Hamada Hiromi, Osaka Naoyuki, Yamamoto Ryo, Tsunoda Kazumasa, Nakano Hirofumi, Watanabe Kimio, Zhu Wan-Jun, Maruyama Yukio, Terawaki Hiroyuki, Kabayama Shigeru, Nakazawa Ryoichi, Miyazaki Mariko, Ito Sadayoshi, PLOS ONE, 2017. This observational study examined Possible clinical effects of molecular hydrogen (H2) delivery during hemodialysis in chronic dialysis patients: Interim analysis in a 12 month observation. The abstract describes Human participants. The abstract reports: The data indicates E-HD could have substantial clinical benefits beyond conventional HD therapy, and support the rationale to conduct clinical trials of H2 application…. This is an automated editorial draft based on the abstract and requires source review before publication.
Molecular hydrogen kidney health study 2017 masaaki overview
It is supposed that enhanced oxidative stress and inflammation are involved with the poor clinical outcomes in patients on chronic dialysis treatment. Recent studies… Because this is human clinical evidence, relevance depends on participant selection, controls, sample size, treatment duration, adherence, outcome measures, and replication.
Study design and hydrogen intervention
Publication type: Observational study. Evidence type: Human clinical evidence. Research model or population: Human participants. Blinding: Unknown. Control status: Unknown.
Delivery method: Other or not reported. Hydrogen concentration: 80 ppb.
Reported findings and scientific interpretation
For this molecular hydrogen kidney health study 2017 masaaki, the study record reports the following: The abstract reports: The data indicates E-HD could have substantial clinical benefits beyond conventional HD therapy, and support the rationale to conduct clinical trials of H2 application…
These findings should be interpreted as one piece of evidence rather than as a stand-alone medical conclusion. Results can be influenced by the research model, study design, treatment protocol, sample size, outcome selection, statistical methods, and whether the findings have been independently reproduced.
How this research record was prepared
H2HUBB organizes bibliographic details, study design information, intervention data, outcomes, limitations, and safety notes from the available scientific source. Automated classification supports database organization, but it does not replace critical reading of the complete paper. Source identifiers, evidence labels, and delivery-method fields are retained so readers can verify the record and compare it with related publications. A missing field means the information was unavailable or not reported in the structured source; it should not be treated as a negative finding.
Limitations, safety, and original source
Limitations: The abstract alone may not report all methodological limitations; full-text review is required.
Safety: The abstract did not provide detailed safety or adverse-event information.
This H2HUBB page is an educational research record, not medical advice. Review the original scientific source for the complete methods and results. Continue exploring the H2HUBB Molecular Hydrogen Research Library to compare evidence types, delivery methods, and related topics.