Hydrogen: another gas with therapeutic potential.
James F George, Anupam Agarwal · Kidney international · 2010
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In rats, they demonstrate that the addition of hydrogen to the drinking water In a decrease in the severity of CAN and increased graft survival, and they provide evidence that the mechanism of action could be due to a reduction in reactive oxygen species. These results are preclinical and suggest molecular hydrogen's therapeutic potential in the condition studied. Further human research is needed to establish clinical effectiveness.
What the Researchers Studied
The study examined rats.
How Molecular Hydrogen Was Used
Molecular hydrogen was administered as cardinal and colleagues describe the use of molecular hydrogen, the most abundant molecule in the universe, as a treatment for chronic allograft nephropathy (can) in a rat model of kidney transplantation. they demonstrate that the addition of hydrogen to the drinking water results in a decrease in the severity of can and increased graft survival, and they provide evidence that the mechanism of action could be due to a reduction in reactive oxygen species.
What the Researchers Found
They demonstrate that the addition of hydrogen to the drinking water In a decrease in the severity of CAN and increased graft survival, and they provide evidence that the mechanism of action could be due to a reduction in reactive oxygen species.
H₂ Mechanisms / Biological Findings
They demonstrate that the addition of hydrogen to the drinking water results in a decrease in the severity of CAN and increased graft survival, and they provide evidence that the mechanism of action could be due to a reduction in reactive oxygen species.
Authors’ Conclusion
A distinct authors’ conclusion was not available in the source material reviewed by H2HUBB.