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Review or synthesisNarrative reviewOther or not reported

Hydrogen Therapy in Cardiovascular and Metabolic Diseases: from Bench to Bedside.

Yaxing Zhang, Sihua Tan, Jingting Xu, Tinghuai Wang · Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2018

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H2HUBB Research Library branded molecular hydrogen research image
Primary topic Cardiovascular Health
Evidence type Review or synthesis
Publication type Narrative review
Hydrogen method Other or not reported

H2HUBB TAKEAWAY

This narrative review examined the available evidence on molecular hydrogen. Delivery of H₂ by various strategies improves cardiometabolic diseases, including atherosclerosis, vascular injury, ischemic or hypertrophic ventricular remodeling, intermittent hypoxia- or heart transplantation-induced heart injury, obesity and diabetes in animal models or in clinical trials. The reviewed evidence supports molecular hydrogen's therapeutic potential. Additional well-designed studies are needed to clarify clinical safety and effectiveness.

What the Review Examined

The review examined hydrogen Therapy in Cardiovascular and Metabolic Diseases: from Bench to Bedside.

Main Findings Across the Literature

Hydrogen (H₂) is colorless, odorless, and the lightest of gas molecules. Studies in the past ten years have indicated that H₂ is extremely important in regulating the homeostasis of the cardiovascular system and metabolic activity. Delivery of H₂ by various strategies improves cardiometabolic diseases, including atherosclerosis, vascular injury, ischemic or hypertrophic ventricular remodeling, intermittent hypoxia- or heart transplantation-induced heart injury, obesity and diabetes in animal models or in clinical trials. The purpose of this review is to summarize the physical and chemical properties of H₂, and then, the functions of H₂ with an emphasis on the therapeutic potential and molecular mechanisms involved in the diseases above.

Authors’ Conclusion

A distinct authors’ conclusion was not available in the source material reviewed by H2HUBB.

CONTINUE EXPLORING

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