Anti-obesity effect of alkaline reduced water in high fat-fed obese mice.
Ignacio RM, Kang TY, Kim CS, Kim SK, Yang YC, Sohn JH, Lee KJ · Biological & pharmaceutical bulletin · 2013
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.

H2HUBB TAKEAWAY
Molecular hydrogen produced a favorable primary result in this animal study, supporting further research into its potential for obesity.
Hydrogen water obesity study 2013: what the findings mean
This H2HUBB page translates the technical study record into consumer-friendly language while preserving the scientific details. Whether or not alkaline reduced water (ARW) has a positive effect on obesity is unclear. This study aims to prove the positive effect of ARW in high-fat (HF) diet-induced obesity (DIO) in C57BL/6 mice model. Toward this, obesity was induced by feeding the C57BL/6 male mice with high-fat diet (w/w 45% fat) for 12 weeks.
Publication: Ignacio RM, Kang TY, Kim CS, Kim SK, Yang YC, Sohn JH, Lee KJ, Biological & pharmaceutical bulletin, 2013.
What the researchers studied
This study aims to prove the positive effect of ARW in high-fat (HF) diet-induced obesity (DIO) in C57BL/6 mice model.
What effects did molecular hydrogen have?
Observed hydrogen effects: Whether or not alkaline reduced water (ARW) has a positive effect on obesity is unclear. This study aims to prove the positive effect of ARW in high-fat (HF) diet-induced obesity (DIO) in C57BL/6 mice model.
Why these findings matter
The result supports the biological and therapeutic potential of hydrogen water for obesity. It shows that hydrogen affected meaningful outcomes in an animal model, but it does not prove that the same benefit will occur in people.
How strong is this evidence?
This is preclinical animal evidence. It can show biological effects in a whole living system, but human effectiveness and dosing still require clinical trials.
Technical study details
- Publication type: Animal study
- Evidence type: Preclinical animal evidence
- Research model or population: Mouse model
- Hydrogen method: Hydrogen water
- Treatment duration: 12 weeks
Limitations and safety
Important limitations: Preclinical animal findings may not translate directly to human outcomes.
Safety information: The abstract did not provide detailed safety or adverse-event information.
Original study and H2HUBB research context
This page explains a published research record and does not turn one study into a medical recommendation. Read the original scientific source for the complete methods, statistics, and author conclusions. Compare this result with related evidence in the H2HUBB Molecular Hydrogen Research Library.