Metal-based micro/nanomaterials for hydrogen therapy and their biomedical applications.
Yu Wang, Haoyu Wang, Handan Zhang, Tao Liu, Xin Chen · Nanoscale · 2025
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Independent study record
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H2HUBB TAKEAWAY
This narrative review examined the available evidence on molecular hydrogen. The challenges and limitations of metal-based micro/nanomaterials for hydrogen therapy are discussed, while providing forward-looking recommendations for future research and development directions in this field. The reviewed evidence supports molecular hydrogen's therapeutic potential. Additional well-designed studies are needed to clarify clinical safety and effectiveness.
What the Review Examined
The review examined metal-based micro/nanomaterials for hydrogen therapy and their biomedical applications.
Main Findings Across the Literature
Hydrogen therapy, as an emerging and promising therapeutic strategy, utilizes the ability of hydrogen to selectively scavenge reactive oxygen species, exerting biological effects such as antioxidant, anti-inflammatory, anti-tumor and antibacterial, and showing significant therapeutic effects on many oxidative stress/inflammatory related diseases, and consequently has attracted extensive attention for clinical/preclinical studies.
Authors’ Conclusion
A distinct authors’ conclusion was not available in the source material reviewed by H2HUBB.
Areas of Agreement or Uncertainty
The challenges and limitations of metal-based micro/nanomaterials for hydrogen therapy are discussed, while providing forward-looking recommendations for future research and development directions in this field.
Limitations Reported by the Authors
The challenges and limitations of metal-based micro/nanomaterials for hydrogen therapy are discussed, while providing forward-looking recommendations for future research and development directions in this field.