Molecular Hydrogen as a Neuroprotective Agent.
Masumi Iketani, Ikuroh Ohsawa · Current neuropharmacology · 2017
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
This narrative review examined the available evidence on molecular hydrogen. Recently, it has been reported that molecular hydrogen (H₂) functions as an antioxidant and anti-inflammatory agent. The reviewed evidence supports molecular hydrogen's therapeutic potential. Additional well-designed studies are needed to clarify clinical safety and effectiveness.
What the Review Examined
The review examined molecular Hydrogen as a Neuroprotective Agent.
Main Findings Across the Literature
Recently, it has been reported that molecular hydrogen (H₂) functions as an antioxidant and anti-inflammatory agent. The routes of H₂ administration in animal model and human clinical studies are roughly classified into three types, inhalation of H₂ gas, drinking H₂-dissolved water, and injection of H₂-dissolved saline. This review discusses some of the remarkable progress that has been made in the research of H₂ use for neurological disorders, such as cerebrovascular diseases, neurodegenerative disorders, and neonatal brain disorders. Although most neurological disorders are currently incurable, these studies suggest the clinical potential of H₂ administration for their prevention, treatment, and mitigation.
H₂ Mechanisms / Biological Findings
Recently, it has been reported that molecular hydrogen (H₂) functions as an antioxidant and anti-inflammatory agent.
Authors’ Conclusion
The authors concluded that although most neurological disorders are currently incurable, these studies suggest the clinical potential of H₂ administration for their prevention, treatment, and mitigation.