Parkinson’s disease may be due to failure of melanin in the Substantia Nigra to produce molecular hydrogen from dissociation of water, to protect the brain from oxidative stress.
Steven Brenner · Medical hypotheses · 2014
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Independent study record
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H2HUBB TAKEAWAY
Parkinson's disease may be due to failure of melanin in the Substantia Nigra to produce molecular hydrogen from dissociation of water, to protect the brain from oxidative stress. This source-grounded publication contributes evidence relevant to molecular hydrogen and is retained in a transparent general research category when a more specific study design is not supported by the indexed record.
What the Publication Examined
Parkinson's disease may be due to failure of melanin in the Substantia Nigra to produce molecular hydrogen from dissociation of water, to protect the brain from oxidative stress.
How Molecular Hydrogen Was Addressed
Melanin, a hybrid electronic/ionic conductor may have the potential to split the water molecule into molecular hydrogen and molecular oxygen. Molecular hydrogen is an antioxidant and may be instrumental in preventing the excessive oxidation leading to Parkinson's disease. Melanin, located in the Substantia Nigra, deteriorates in Parkinson's disease so may be related to the development and progression of the disease, since molecular hydrogen would no longer be generated as it deteriorates.
What the Publication Reported
Melanin, a hybrid electronic/ionic conductor may have the potential to split the water molecule into molecular hydrogen and molecular oxygen.