Post-COVID-19 fatigue: A systematic review.
Jian Joli, Patrizia Buck, Stephan Zipfel, Andreas Stengel · Frontiers in psychiatry · 2022
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
In participants, molecular hydrogen (H₂) inhalation had beneficial health effects in terms of improved physical (6-min walking test) and respiratory function in patients with post-COVID-19. These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence fatigue-related outcomes.
What the Findings Mean
H2HUBB reviewed how molecular hydrogen was evaluated in this publication and summarizes the source-grounded findings below. Molecular hydrogen (H₂) inhalation had beneficial health effects in terms of improved physical (6-min walking test) and respiratory function in patients with post-COVID-19.
What the Researchers Studied
The study used a systematic review.
What Effects Did Molecular Hydrogen Have?
Molecular hydrogen (H₂) inhalation had beneficial health effects in terms of improved physical (6-min walking test) and respiratory function in patients with post-COVID-19. Botek et al. ( 27 ) used in their randomized, single-blind, placebo-controlled study molecular hydrogen (H₂ ) as a therapeutic gas for 50 patients with post-COVID-19 with a follow-up of 33 days because it has antioxidative, anti-inflammatory, anti-apoptotic and anti-fatigue properties ( 45 – 47 ).
Why These Findings Matter
These findings add human evidence supporting molecular hydrogen's therapeutic potential to influence fatigue-related outcomes and contribute to the growing body of molecular-hydrogen research.
How Strong Is This Evidence?
This is human clinical evidence from a systematic review. H2HUBB interprets the findings in the context of the study design, sample, comparator, and measured outcomes rather than using one publication as a verdict on hydrogen therapy.
Technical Study Details
H2HUBB classifies this publication as human clinical study with human clinical evidence. The reported sample size was 629. The study used a systematic review.
Limitations and Safety
No separate limitations or safety findings were identified in the current-study source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.