Recent advances in chemically controlled molecular hydrogen generation for biomedical applications
Yu Zhao, Zhengbo Wang, Hongbin Li, Feng Cheng · Materials Today Chemistry · 2026
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
The review reports that These chemically controlled strategies enable selective regulation of highly reactive oxygen and nitrogen species.
What the Researchers Studied
Source-reported study description: Molecular hydrogen (H2), once regarded as a biologically inert gas, has recently emerged as a chemically active mediator with unique redox selectivity and excellent biocompatibility.
Source-reported study description: In contrast to conventional gas administration, the biomedical efficacy of H2 is fundamentally governed by its chemical generation pathways, reaction kinetics, and spatiotemporal controllability.
What the Study Found
The authors reported: Recent advances in chemistry-driven H2 production—encompassing electrocatalytic, photocatalytic, sonocatalytic, piezocatalytic, chemical reaction–based, and biohybrid approaches—have enabled precise regulation of hydrogen generation at interfaces and within complex biological environments.
What the Findings Mean
The authors concluded/reported: These chemically controlled strategies enable selective regulation of highly reactive oxygen and nitrogen species.
Study Details
Publication type: narrative_review
Evidence source level: B_ABSTRACT
Original scholarly source: https://doi.org/10.1016/j.mtchem.2026.103813