Research progress on the preventive and therapeutic effects of hydrogen in oxidative stress-induced pulmonary diseases
Zhilong Liu, Pei Zhao, Yufeng Kang, Wenjun Yan · Zhonghua wei zhong bing ji jiu yi xue · 2026
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
This narrative review examined recent research findings on the therapeutic application of H₂ in oxidative stress-related pulmonary diseases, aiming to provide theoretical foundations and research directions for the clinical application of H₂ in the prevention and treatment of lung diseases. Traditional antioxidants exhibit limitations due to their non-specific actions and safety concerns, whereas hydrogen (H₂), as a novel selective antioxidant, can readily cross the blood-brain barrier and blood-tissue barriers to rapidly reach target tissues, effectively eliminating ROS. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
What the Findings Mean
H2HUBB reviewed this publication as a synthesis of molecular-hydrogen research and summarizes the outcomes emphasized by the authors. This review summarizes recent research findings on the therapeutic application of H₂ in oxidative stress-related pulmonary diseases, aiming to provide theoretical foundations and research directions for the clinical application of H₂ in the prevention and treatment of lung diseases.
What the Researchers Studied
The authors reviewed recent research findings on the therapeutic application of H₂ in oxidative stress-related pulmonary diseases, aiming to provide theoretical foundations and research directions for the clinical application of H₂ in the prevention and treatment of lung diseases.
What Effects Did Molecular Hydrogen Have?
This review summarizes recent research findings on the therapeutic application of H₂ in oxidative stress-related pulmonary diseases, aiming to provide theoretical foundations and research directions for the clinical application of H₂ in the prevention and treatment of lung diseases.
Why These Findings Matter
The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
How Strong Is This Evidence?
This is review or synthesis evidence (narrative review).
Technical Study Details
H2HUBB classifies this publication as narrative review with review or synthesis evidence. The study used a narrative review.
Limitations and Safety
Reported limitations: Traditional antioxidants exhibit limitations due to their non-specific actions and safety concerns, whereas hydrogen (H₂), as a novel selective antioxidant, can readily cross the blood-brain barrier and blood-tissue barriers to rapidly reach target tissues, effectively eliminating ROS.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base.