Utilization of the liquid one carbon feedstocks methanol and formate for acetogenic bioproduction of chemicals and fuels.
Pettinato E, Hocq R, Pflügl S · Bioresource technology · 2025
Research-use notice
Independent study record
Each H2HUBB study page organizes source-linked research details for educational use. Interpretation should remain proportional to the study design, population, controls, and limitations.
H2HUBB TAKEAWAY
This narrative review examined the available molecular-hydrogen literature. Acetogenic bacteria are strictly anaerobic microorganisms that can grow autotrophically on molecular hydrogen or use methanol, formate, and carbon monoxide as their sole carbon and energy sources via the Wood-Ljungdahl pathway, the most energetically efficient carbon fixation pathway known to date. The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
What the Findings Mean
H2HUBB reviewed this publication as a synthesis of molecular-hydrogen research and summarizes the outcomes emphasized by the authors. Acetogenic bacteria are strictly anaerobic microorganisms that can grow autotrophically on molecular hydrogen or use methanol, formate, and carbon monoxide as their sole carbon and energy sources via the Wood-Ljungdahl pathway, the most energetically efficient carbon fixation pathway known to date.
What the Researchers Studied
The authors reviewed utilization of the liquid one carbon feedstocks methanol and formate for acetogenic bioproduction of chemicals and fuels.
What Effects Did Molecular Hydrogen Have?
Acetogenic bacteria are strictly anaerobic microorganisms that can grow autotrophically on molecular hydrogen or use methanol, formate, and carbon monoxide as their sole carbon and energy sources via the Wood-Ljungdahl pathway, the most energetically efficient carbon fixation pathway known to date.
Why These Findings Matter
The reviewed evidence adds support for molecular hydrogen's therapeutic potential across the conditions, mechanisms, or outcomes examined.
How Strong Is This Evidence?
This is review or synthesis evidence (narrative review).
Technical Study Details
H2HUBB classifies this publication as narrative review with review or synthesis evidence. The study used a narrative review.
Limitations and Safety
No separate limitations or safety findings were identified in the current-study source text available to H2HUBB.
Original Study and H2HUBB Research Context
H2HUBB presents this source-grounded research record as one contribution to the broader molecular-hydrogen evidence base. The original scholarly source is available at https://europepmc.org/article/MED/40383309.